Results 131 to 140 of about 4,466,693 (321)

Regional differences in gallbladder cancer pathogenesis: Insights from a multi‐institutional comparison of tumor mutations

Cancer, 2018
Although rare in the United States, gallbladder cancer (GBCA) is a common cause of cancer death in some parts of the world. To investigate regional differences in pathogenesis and outcomes for GBCA, tumor mutations were analyzed from a sampling of ...
R. Narayan, J. Creasy, D. Goldman, M. Gönen, C. Kandoth, Ritika Kundra, D. Solit, G. Askan, D. Klimstra, O. Basturk, P. Allen, V. Balachandran, M. D'Angelica, R. DeMatteo, J. Drebin, T. Kingham, Amber L. Simpson, G. Abou-Alfa, J. Harding, E. O’Reilly, J. M. Butte, R. Matsuyama, I. Endo, W. Jarnagin   +23 more
semanticscholar   +1 more source

A Large‐Scale Retrospective Study of Serum Des‐Gamma‐Carboxy Prothrombin as a Diagnostic Marker of HCC: Effect of Liver Function on Specificity

Journal of Clinical Laboratory Analysis, EarlyView.
Serum DCP may serve as an optimal biomarker for the diagnosis of HCC, but its accuracy appears to be influenced by liver function. The serum DCP may also serve as a biomarker for liver resection and interventional therapy of HCC, but is not promising for systemic treatment. ABSTRACT Background This retrospective multicenter study is aimed at evaluating
Hongying Bu, Weijia Luo, Wenli Tao, Chen Dong, Meifang Wang, Xu Ye, Xi Zeng, Boqing Wang, Chang Liu, Qi Yu, Deliang Cao, Hongyu Deng, Yuemin Nan   +12 more
wiley   +1 more source

MicroRNA-34a-5p: A pivotal therapeutic target in gallbladder cancer

Molecular Therapy: Oncology
Gallbladder cancer incidence has been increasing globally, and it remains challenging to expect long prognosis with the current systemic chemotherapy.
Takashi Oda, Koichiro Tsutsumi, Taisuke Obata, Eijiro Ueta, Tatsuya Kikuchi, Soichiro Ako, Yuki Fujii, Tatsuhiro Yamazaki, Daisuke Uchida, Kazuyuki Matsumoto, Shigeru Horiguchi, Hironari Kato, Hiroyuki Okada, Ryota Chijimatsu, Motoyuki Otsuka   +14 more
doaj  

The rare histological forms of gallbladder cancer [PDF]

Морфологія, 2011
In the practice of surgeons meet the rare forms of gallbladder cancer, with atypical clinical course. The aim of ourinvestigation was revealed peculiarity of clinical display the rarely forms of gallbladder cancer.
Lytvynenko M.V., Rosha L.G., Chetverykov S.G., Vododuk V.U., Sherstiuk S.A., Katsap A.V.   +5 more
doaj  

Computational methods for cancer driver discovery: A survey [PDF]

arXiv, 2020
Motivation: Uncovering the genomic causes of cancer, known as cancer driver genes, is a fundamental task in biomedical research. Cancer driver genes drive the development and progression of cancer, thus identifying cancer driver genes and their regulatory mechanism is crucial to the design of cancer treatment and intervention.
arxiv  

Treatment of advanced gallbladder cancer: A SEER‐based study

Cancer Medicine, 2019
The treatment of advanced gallbladder cancer (GBC) remains controversial. Therefore, the purpose of this study was to explore treatment choices for advanced GBC.
W. Mao, Fang Deng, Dong-yan Wang, Li Gao, Xiuquan Shi   +4 more
semanticscholar   +1 more source

Mortality and cardiovascular disease after cholecystectomy in type 2 diabetes: A nationwide longitudinal cohort study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background The long‐term effects of cholecystectomy on mortality and cardiovascular disease (CVD) in patients with diabetes have not been evaluated. In the present study, we investigated the longitudinal effects of cholecystectomy on mortality and CVD in a population‐based cohort with type 2 diabetes (T2D). Methods In total, 2 216 930 national
Han Na Jung, Ji Hye Heo, Eun Roh, Kyung‐Do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm   +6 more
wiley   +1 more source

Choledochoduodenal fistula presenting with pneumobilia in a patient with gallbladder cancer: a case report

Journal of Medical Case Reports, 2012
Introduction Spontaneous biliary tract fistulas are rare entities. Most of them are associated with long-standing gallstones (especially common bile duct stones, or recurrent biliary tract infections), some with more uncommon diseases such as gallbladder
Dadzan Elham, Akhondi Hossein
doaj   +1 more source

Major hepatectomy with or without pancreatoduodenectomy for advanced gallbladder cancer

British Journal of Surgery, 2019
The indications for major hepatectomy for gallbladder cancer either with or without pancreatoduodenectomy remain controversial. The clinical value of these extended procedures was evaluated in this study.
Takashi Mizuno, T. Ebata, Y. Yokoyama, T. Igami, J. Yamaguchi, S. Onoe, N. Watanabe, M. Ando, Masato Nagino   +8 more
semanticscholar   +1 more source

Comparable impact of lymph node metastases in T2 gallbladder cancer on postoperative prognosis irrespective of the extent of the metastases: A retrospective analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Lymph node metastases beyond the hepatoduodenal ligament are sometimes encountered in locally limited T2 gallbladder cancer (GBCA). However, the incidence and impact on prognosis remain unclear. Methods This was a retrospective multi‐institutional study of patients who underwent surgical resection for GBCA from 2002 to 2022.
Yoji Kishi, Teiichi Sugiura, Takashi Mizuno, Hiromichi Ito, Yu Takahashi, Takehiro Noji, Yuta Abe, Shimpei Otsuka, Shoji Kawakatsu, Asayo Kato, Masayuki Tanaka, Tomoki Ebata, Satoshi Hirano   +12 more
wiley   +1 more source