Phase I Clinical Trial of CVL218, a Novel PARP1/2 Inhibitor, in Patients with Advanced Solid Tumors
CVL218, a PARP1/2 inhibitor, was generally well tolerated and safe in solid tumors. It showed potential antitumor activity in patients treated with the recommended dose (700 mg BID). ABSTRACT CVL218, a novel poly ADP‐ribose polymerase (PARP1/2) inhibitor, has strong PARP1/2 selective inhibitory activity and high oral bioavailability. We aimed to assess
Zihong Chen+12 more
wiley +1 more source
GDF15 promotes gallbladder cancer progression by activating the NF-κB mediated Vascular Endothelial Growth Factor A (VEGFA) expression. [PDF]
Joo M, Lee HJ, Kim JM.
europepmc +1 more source
Prediction Model for Estimating the Survival Benefit of Adjuvant Radiotherapy for Gallbladder Cancer [PDF]
Samuel J. Wang+5 more
openalex +1 more source
Social mechanics of gifting bear bile in Việt Nam
Abstract The illegal wildlife trade is a major cause of global diversity loss. In Southeast Asia and particularly in Việt Nam, the consumption of wildlife products is mostly driven by demand for food and traditional medicine products. One key example of this in Việt Nam is the use of bear bile. While bear bile is one of the most well‐researched illegal
Elizabeth Oneita Davis+2 more
wiley +1 more source
Risk factors of gallbladder cancer in Nepal: A case control study. [PDF]
Thakur C+5 more
europepmc +1 more source
Frozen section and permanent diagnoses of the bile duct margin in gallbladder and bile duct cancer
Kengo Shirahane+8 more
openalex +1 more source
Artificial intelligence (AI)‐driven simplification of medical reports holds promise for improving patient education. However, careful attention must be paid to ensuring accuracy and completeness. Use of AI technologies in healthcare will continue to expand but will require rigorous oversight and ongoing research to fully realize their potential in ...
Maximilian Riedel+6 more
wiley +1 more source
NUF2 and NEK2 promote malignant progression of gallbladder cancer by remodeling the extracellular matrix. [PDF]
Gao M, Ye P, Zhang Y, Guo Y, Xu J.
europepmc +1 more source
Epidemiology and prognostic factors of gallbladder cancer in México
Ricardo Mondragón–Sánchez+5 more
openalex +1 more source