Results 91 to 100 of about 38,138 (190)
ABSTRACT Introduction Lenvatinib plus pembrolizumab is a standard first‐line therapy for advanced renal cell carcinoma (RCC), and acute acalculous cholecystitis is a rare adverse event. Case Presentation A 60‐year‐old woman with metastatic TFE3‐positive non–clear cell RCC, classified as poor risk by the International Metastatic RCC Database Consortium (
Erika Soga +9 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog
Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann +6 more
wiley +1 more source
This study demonstrates multiple primary malignancies (MPMs) occur in 4.01% of gastric cancer patients and most commonly involve the esophagus, colorectum, and lung. Distinct differences are observed between synchronous and metachronous cases. These findings establish a clinical and epidemiological framework to inform future investigations into MPMs in
Guiling Zhu +6 more
wiley +1 more source
BackgroundGallbladder cancer is a highly lethal biliary tract malignancy. Among them, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN), particularly those containing large cell neuroendocrine carcinoma (LCNEC) components, are extremely rare and ...
Quanlei Wang +20 more
doaj +1 more source
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer
ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang +4 more
wiley +1 more source
Individuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Veronica Fitzpatrick +6 more
wiley +1 more source
Estimating Cancer Prevalence in Japan: Insights from the Osaka Cancer Registry ABSTRACT Owing to improved prognosis, cancer survivors are a growing population; however, little is known about their prevalence in Asian countries. This study estimated the prevalence and characteristics of cancer survivors in Japan, including long‐term survivors.
Haruka Kudo +7 more
wiley +1 more source
ABSTRACT Aim Upper gastrointestinal bleeding (UGIB) is associated with an unfavorable outcome in cancer patients. In patients with biliary tract cancer (BTC), data on the incidence, management, and prognostic implications of UGIB are limited. This study investigated the prevalence, treatment efficacy, and prognostic factors associated with UGIB in BTC.
Jan Christoph Schumacher +8 more
wiley +1 more source

