Results 91 to 100 of about 38,138 (190)

A Case of Acalculous Cholecystitis During Lenvatinib Plus Pembrolizumab Therapy for Advanced Renal Cell Carcinoma

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Lenvatinib plus pembrolizumab is a standard first‐line therapy for advanced renal cell carcinoma (RCC), and acute acalculous cholecystitis is a rare adverse event. Case Presentation A 60‐year‐old woman with metastatic TFE3‐positive non–clear cell RCC, classified as poor risk by the International Metastatic RCC Database Consortium (
Erika Soga   +9 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann   +6 more
wiley   +1 more source

Multiple Primary Malignancies in Patients With Gastric Cancer: A Retrospective Study in National Cancer Center of China

open access: yesCancer Innovation, Volume 5, Issue 3, June 2026.
This study demonstrates multiple primary malignancies (MPMs) occur in 4.01% of gastric cancer patients and most commonly involve the esophagus, colorectum, and lung. Distinct differences are observed between synchronous and metachronous cases. These findings establish a clinical and epidemiological framework to inform future investigations into MPMs in
Guiling Zhu   +6 more
wiley   +1 more source

Case report: A challenging case of stage IVB mixed neuroendocrine-non-neuroendocrine neoplasm of the gallbladder treated with extended radical resection including portal vein reconstruction

open access: yesFrontiers in Oncology
BackgroundGallbladder cancer is a highly lethal biliary tract malignancy. Among them, mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN), particularly those containing large cell neuroendocrine carcinoma (LCNEC) components, are extremely rare and ...
Quanlei Wang   +20 more
doaj   +1 more source

Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang   +4 more
wiley   +1 more source

Cancer Prevalence Among Large Cohort of Individuals With Down Syndrome: Implications for Screening Guidelines

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
Individuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Veronica Fitzpatrick   +6 more
wiley   +1 more source

Prevalence of Cancer Survivors in 2019 Among Patients Diagnosed Between 1975 and 2019: A Population‐Based Study in Japan

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
Estimating Cancer Prevalence in Japan: Insights from the Osaka Cancer Registry ABSTRACT Owing to improved prognosis, cancer survivors are a growing population; however, little is known about their prevalence in Asian countries. This study estimated the prevalence and characteristics of cancer survivors in Japan, including long‐term survivors.
Haruka Kudo   +7 more
wiley   +1 more source

Acute Upper Gastrointestinal Bleeding is Associated With Poor Prognosis in Patients With Biliary Tract Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Aim Upper gastrointestinal bleeding (UGIB) is associated with an unfavorable outcome in cancer patients. In patients with biliary tract cancer (BTC), data on the incidence, management, and prognostic implications of UGIB are limited. This study investigated the prevalence, treatment efficacy, and prognostic factors associated with UGIB in BTC.
Jan Christoph Schumacher   +8 more
wiley   +1 more source

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