Results 81 to 90 of about 38,138 (190)

Codocytosis in the Dog: 345 Cases (2020–2022)

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker   +5 more
wiley   +1 more source

A Multicenter Phase II Trial of Gemcitabine Plus Oxaliplatin in Unresectable Gallbladder Cancer

open access: yesGut and Liver, 2013
Background/AimsNo standard chemotherapy has been established for advanced gallbladder cancer. The authors studied the activity and tolerability of a gemcitabine and oxaliplatin (GEMOX) combination in unresectable gallbladder cancer (GBC).Methods : Adult ...
doaj   +1 more source

Cohort Study: Risk of Gallstones and Biliary Complications With Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes. [PDF]

open access: yesUnited European Gastroenterol J
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely prescribed for type 2 diabetes mellitus (T2DM) because of their benefits in glycemic control, weight reduction, and cardiovascular outcomes. This study evaluated the risk of gallbladder disease among diabetic patients treated with GLP‐1 RAs.
Eldesouki MH   +7 more
europepmc   +2 more sources

Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial (January 2021 to November 2022). Setting University teaching hospital.
Nadine Jones   +2 more
wiley   +1 more source

Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma

open access: yesClinical Medicine Insights: Case Reports
Biliary tract carcinomas (BTC) are malignant epithelial neoplasms subdivided anatomically into: gallbladder carcinomas and carcinomas of the bile duct or cholangiocarcinomas (CCA); including intrahepatic, hilar/perihilar, and distal CCA.
Derqaoui Sabrine   +6 more
doaj   +1 more source

Phase I/II Prospective Study on Endoscopic Ultrasound‐Guided Hepaticogastrostomy as Primary Drainage for Unresectable Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Various drainage methods have been used for unresectable malignant hilar biliary obstruction (MHBO). However, controlling cholangitis and obstructive jaundice is still challenging. We performed a phase I/II study of endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) as primary drainage for MHBO.
Tomoki Ogata   +7 more
wiley   +1 more source

Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Advances in chemotherapy have increased survival in biliary tract cancer patients, and reports of the effectiveness of neoadjuvant therapy are emerging. Accordingly, developing optimal drainage strategies under chemotherapy is important.
Katsuhiko Sato   +8 more
wiley   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken   +4 more
wiley   +1 more source

Neuroendocrine Transformation Without PSA Elevation in High‐Risk Metastatic Castration‐Sensitive Prostate Cancer Under Androgen Receptor Signaling Inhibition: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Neuroendocrine prostate cancer is a rare and highly aggressive variant of prostate cancer with a poor prognosis. We report a case in which metastatic castration‐sensitive prostate cancer directly transformed into neuroendocrine prostate cancer without a corresponding increase in prostate‐specific antigen.
Yoshihiro Nakagami   +9 more
wiley   +1 more source

Histopathological Profile of Cholecystectomy Specimens at a Tertiary Care Center: A Retrospective Study

open access: yesJournal of the Scientific Society
Introduction: Gallbladder is one of the most frequently received specimens in any histopathology laboratory. Its diseases may present with a varied spectrum ranging from congenital anomalies, cholelithiasis, and inflammatory or noninflammatory lesions to
Udita Bajaj   +3 more
doaj   +1 more source

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