Results 111 to 120 of about 19,127 (267)

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

European Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano, Emmanuel Somm, François R. Jornayvaz, Nicolas Vuilleumier   +3 more
wiley   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Clinicopathologic and Molecular Features of Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gallbladder

, 2020
Mouyed Alawad, Raavi Gupta, M.A. Haseeb, F. Charles Brunicardi   +3 more
openalex   +2 more sources

Leiomyoma Causing Disease in a Wild Adriatic Sturgeon (Acipenser naccarii , Bonaparte, 1836)

Journal of Fish Diseases, EarlyView.
ABSTRACT The Adriatic sturgeon, Acipenser naccarii, is an endemic species to the Adriatic Sea basin classified as critically endangered according to the IUCN Red List. Limited information is available regarding the health status and diseases affecting this species, particularly in the wild.
A. Marsella, T. Pretto, C. Samassa, P. Tedesco, F. Pascoli, L. Congiu, A. Gustinelli, F. Borghesan, A. Toffan   +8 more
wiley   +1 more source

Histopathological Profile of Cholecystectomy Specimens at a Tertiary Care Center: A Retrospective Study

Journal of the Scientific Society
Introduction: Gallbladder is one of the most frequently received specimens in any histopathology laboratory. Its diseases may present with a varied spectrum ranging from congenital anomalies, cholelithiasis, and inflammatory or noninflammatory lesions to
Udita Bajaj, Dimple Kalsi, Preeti Bajaj, Sheela Chikhalikar   +3 more
doaj   +1 more source

Comparison of 5‐Fluorouracil/Leucovorin and Capecitabine as Adjuvant Therapies in Biliary Tract Cancer

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background The prognosis of biliary tract cancer (BTC) is poor, and recurrence rates remain high even after curative resection. This study aimed to compare the efficacy and safety of capecitabine and 5‐fluorouracil/leucovorin (FL) as adjuvant treatments following curative resection in patients with BTC.
Tae Seung Lee, Young Hoon Choi, Jun Yeol Kim, Myeong Hwan Lee, Kyu‐Hyun Paik, In Rae Cho, Woo Il Kwon, Sang Hyub Lee, In Seok Lee, Myung Ah. Lee, Jin‐Young Jang, Ji Kon Ryu, Yong‐Tae Kim, Woo Hyun Paik   +13 more
wiley   +1 more source

Cholecystokinin: Clinical aspects of the new biology

Journal of Internal Medicine, EarlyView.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

S2095 Mixed Neuroendocrine Non-Neuroendocrine Neoplasm of the Gallbladder With Large Cell Neuroendocrine Carcinoma, Squamous Cell Carcinoma, and Adenocarcinoma Components: Report of a Rare Case

, 2023
Shubhneet Bal, Mohammad A Ahmed-Khan, Fnu Sandeep, Samuel Barasch, Nusrat Fozia Pathan   +4 more
openalex   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Carcinoma adenoescamoso de la vesícula biliar, una rara variedad histológica

Revista Colombiana de Cirugía
El carcinoma adenoescamoso primario de la vesícula biliar es una variante poco conocida e infrecuente de este tipo de neoplasias, cuya etiología y comportamiento siguen constituyendo un enigma. Se trata de una paciente de 45 años de edad con un carcinoma
Katherine Redondo, Saúl Rivero, Karina Ruiz, José Díaz, Daniella Lozano, Luisa Luna   +5 more
doaj