Results 181 to 190 of about 42,809 (327)

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, Volume 599, Issue 23, Page 3524-3536, December 2025.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

RefineCatDiff: Toward High‐Quality Medical Image Segmentation via a Categorical Diffusion Refinement Framework

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 12, December 2025.
This study proposes RefineCatDiff, a refinement framework for high‐quality medical image segmentation. By developing a categorical distribution‐based discrete diffusion process for refinement, the framework aligns well with the characteristics of image segmentation tasks. Experimental results on multiple datasets across different modalities demonstrate
Feng Liu   +8 more
wiley   +1 more source

Primary gallbladder paraganglioma: a case report. [PDF]

open access: yesJ Surg Case Rep
Mawlaalduwilah S   +3 more
europepmc   +1 more source

Spectrometry and Its Application for the Detection of RNA‐Binding Proteins: Advancements, Techniques and Challenges

open access: yesAnalytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Spectrometry is a fascinating field of analytical science that encompasses a range of techniques used to study the interaction between electromagnetic radiation and matter. Through the measurement and analysis of various radiations, spectrometry provides valuable insights into the composition, structure and properties of different substances ...
Mina Moradi   +2 more
wiley   +1 more source

Primary extra-gastrointestinal stromal tumor of the gallbladder: A case report. [PDF]

open access: yesWorld J Gastroenterol
Wang P   +8 more
europepmc   +1 more source

From Gene to Enzyme: Multidimensional Decoding of the GGT Molecular Family and Its Clinical Tumor Diagnosis

open access: yesCancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang   +11 more
wiley   +1 more source

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