Results 211 to 220 of about 42,809 (327)

Biological evaluation of a glucose‐based boron carrier as a potential agent for boron neutron capture therapy

open access: yesInternational Journal of Cancer, Volume 157, Issue 11, Page 2374-2384, 1 December 2025.
What's New? Boron neutron capture therapy (BNCT) is a targeted form of radiation therapy designed to selectively destroy cancer cells. BNCT is not widely used, however, owing in part to challenges involving selective boron delivery to tumors. The present study evaluated the potential of a novel glucoconjugate, 6‐O‐(o‐carboranylmethyl)‐d‐glucopyranose ...
Surachet Imlimthan   +15 more
wiley   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu   +5 more
wiley   +1 more source

[Gallbladder neoplasms].

open access: yesWiadomosci lekarskie (Warsaw, Poland : 1960), 1977
L, Ignaczak, K, Lewicki
openaire   +1 more source

Global, Regional, and National Burden of Cancer in the Elderly Population, 1990–2021: Analysis of Data From the Global Burden of Disease Study 2021

open access: yesMed Research, Volume 1, Issue 3, Page 440-454, December 2025.
ABSTRACT With the global aging trend intensifying, cancer presents a significant health challenge for the elderly. This study aims to assess the prevalence, mortality, and disability‐adjusted life years (DALY) burden of cancer among individuals aged 60–94 worldwide from 1990 to 2021.
Xiaohan Zhu   +4 more
wiley   +1 more source

Salvage Reconstruction With Recycled Flap Pedicles in Head‐and‐Neck Surgery: A Report of Two Cases

open access: yesMicrosurgery, Volume 45, Issue 8, December 2025.
ABSTRACT Free‐flap reconstruction of head‐and‐neck defects is often complicated by a vessel‐depleted neck after prior surgery or radiotherapy. Conventional alternatives—such as using contralateral vessels, distant recipient vessels, or interpositional vein grafts—are technically demanding and associated with additional risks.
Akatsuki Kondo   +3 more
wiley   +1 more source

Application of the Da Vinci Single‐Port (SP) Robot in General Surgery: A First Systematic Review

open access: yesThe International Journal of Medical Robotics and Computer Assisted Surgery, Volume 21, Issue 6, December 2025.
ABSTRACT Introduction Minimally invasive surgery has revolutionized surgical practice by reducing surgical trauma and enhancing recovery. In this context, the da Vinci SP System represents a major technological advancement. This review aims to report its clinical applications in general surgery, evaluating associated outcomes and potential advantages ...
Antonio Cubisino   +2 more
wiley   +1 more source

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