Results 101 to 110 of about 25,963 (247)
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Phenolic compounds in Ecuadorian fruits [PDF]
, 2009 A group of eighteen fruits cultivated in Ecuador were evaluated for their total soluble phenolic compounds and antioxidant activity and attempts were made to identify the group and content of phenolic compounds responsible for the antioxidant activity ...
Vasco, Catalina
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Arthritis Care &Research, EarlyView.Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
, 2017 Xueling Mu,1–3 Chenglin Yan,1–3 Qiwei Tian,1–3 Jiaomin Lin,1–3 Shiping Yang1–3 1Key Laboratory of Resource Chemistry, 2Key Laboratory of Rare Earth Functional Materials, 3Key Laboratory of Molecular Imaging Probes and ...
Mu X, Tian QW, Yan C, Lin J, Yang S
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Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies
Advanced Engineering Materials, EarlyView.Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo +3 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir +5 more
wiley +1 more source
Metabolism of Gallic Acid and Syringic Acid by Pseudomonas putida
Journal of Biological Chemistry, 1972 Cell-free extracts of Pseudomonas putida, grown with syringic acid as carbon source, catalyzed the oxidation of 1 mole of gallate (3,4,5-trihydroxybenzoate) by 1 mole of oxygen to give 2 moles of pyruvate and 1 mole of carbon dioxide. Oxaloacetate, formed as an intermediate in reactions, could be reduced quantitatively when NADH and sufficient malate ...
B F, Tack, P J, Chapman, S, Dagley
openaire +2 more sources
Advanced Engineering Materials, EarlyView.This study shows that superalloys used in aircraft engine disks become much more prone to deformation at high temperatures if they have been strained during manufacturing. This effect increases with the level of prior strain but eventually reaches a limit.
Fabio Machado Alves da Fonseca +9 more
wiley +1 more source