Results 121 to 130 of about 33,356 (238)

Association between triglyceride glucose index-related indices with gallstone disease among US adults

open access: yesLipids in Health and Disease
Background Triglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose-waist circumference (TyG-WC)], represents ...
Chang Fu   +5 more
doaj   +1 more source

Indications for Laparoscopic Cholecystectomy or Oral Dissolution Therapy with Ursodeoxycholic Acid in Symptomatic Gallstone Disease

open access: yesArchives of Clinical and Experimental Surgery, 2014
Unconjugated bilirubin plays an important role in cholesterol gallstone formation. Patients with symptomatic gallstone disease who have high bilirubin plasma levels and/or are homozygous for the rs6742078 TT variant of the bilirubin glucuronidating gene ...
Andrea Cariati   +4 more
doaj   +1 more source

Ceftriaxone-associated nephrolithiasis and gallstone in adults

open access: yes, 2018
Ghodsiyeh Azarkar,1 Motahare Mahi Birjand,2 Alireza Ehsanbakhsh,3 Bita Bijari,1 Mohammad Reza Abedini,4 Masood Ziaee1 1Infectious Disease Research Center, Birjand University of Medical Sciences, Birjand, Iran; 2Student Research Committee, Department of ...
Ehsanbakhsh A   +5 more
core  

Abcb4 Haploinsufficiency Sensitises Mice to a Diet‐Induced PSC‐Like Hepatobiliary Phenotype With Gallstone Formation

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT ABCB4 translocates phospholipids (PL) into bile to buffer the toxicity of bile acids (BA) and free cholesterol (CHOL). While recessively inherited ABCB4 deficiency causes childhood Progressive Familial Intrahepatic Cholestasis type 3, haploinsufficiency has been linked to adult‐onset hepatobiliary diseases.
Eric L. Bell   +6 more
wiley   +1 more source

Mouse models of gallstone disease

open access: yes, 2017
PURPOSE OF REVIEW: The establishment of mouse models of gallstones, and the contribution of mouse models to genetic studies of gallstone disease, as well as the latest advances in the pathophysiology of gallstones from mouse experiments are summarized ...
Min Liu   +9 more
core   +1 more source

ω‐3PUFAs Inhibit Gallbladder Cancer Through Enhancing STK31 Methylation

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
ABSTRACT Gallbladder cancer (GBC) is an aggressive malignancy with limited treatment options. ω‐3PUFAs have known anticancer activity, but their role in GBC remains unclear. The anti‐GBC effects of ω‐3PUFAs (DHA/EPA) were evaluated using in vitro assays and mouse xenograft models.
Shuang‐Xing Li   +16 more
wiley   +1 more source

Dietitian‐led very low‐calorie diet for preoperative rehabilitation in patients with obesity awaiting non‐bariatric elective laparoscopic surgery: A retrospective study

open access: yesNutrition in Clinical Practice, Volume 41, Issue 3, Page 892-904, June 2026.
Abstract Background Obesity increases the risks and complexity of laparoscopic surgeries. Preoperative very low‐calorie diets (VLCDs) can demonstrate significant preoperative weight loss. However, the optimal VLCD duration remains unclear. Excessive loss of muscle mass associated with VLCDs may elevate surgical and postoperative risks. This study aimed
Gerald Wei Shen Wong   +4 more
wiley   +1 more source

Pathophysiology of cholesterol gallstone disease

open access: yes, 1996
The purpose of the present paper is to review the current knowledge about cholesterol gallstone disease. It is generally accepted that the formation of cholesterol gallstone requires three major pathogenic defects, namely, supersaturation, nucleation and
Uribe, M   +3 more
core  

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini   +7 more
wiley   +1 more source

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