Results 1 to 10 of about 45,905 (256)

Factors related to intestine have a role in prevention and treatment for gallstone disease [PDF]

Waike lilun yu shijian, 2023
Gallstone is a common surgical disease. The factors which related to intestine during the process of gallstone formation have attracted increasing attention.
JIANG Zhaoyan, SHEN Weiyi, HU Hai
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Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

Journal of Biomedical Science, 2023
Background Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice.
Weiyi Shen, Wentao Shao, Qihan Wang, Bo Wang, Gang Zhao, Aihua Gu, Zhaoyan Jiang, Hai Hu   +7 more
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Estrogen: risk factor for Xinjiang female patients with gallstone [PDF]

Waike lilun yu shijian, 2021
Objective To investigate estrogen as one of risk factors in women with gallstone in Xinjiang. Methods Estradiol, luteinizing hormone(LH), follicle-stimulating hormone(FSH), testosterone, progesterone, and prolactin in 204 women with gallstone were ...
Azatijiang Ainiwaer, Abuduwaili Aierken, YU Sufu, YU Wenqing, Kelimu
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METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

Cancer Cell International, 2022
Objective N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA).
Jingli Cai, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu   +6 more
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IGF2BP3 drives gallbladder cancer progression by m6A-modified CLDN4 and inducing macrophage immunosuppressive polarization

Translational Oncology, 2023
Introduction: N6-methyladenosine (m6A) is an emerging epigenetic modification, which plays a crucial role in the development of cancer. Nevertheless, the underlying mechanism of m6A-associated proteins and m6A modification in gallbladder cancer remains ...
Jian Qin, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu, Jingli Cai   +7 more
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Free fatty acids and triglyceride change in the gallbladder bile of gallstone patients with pancreaticobiliary reflux

Lipids in Health and Disease, 2021
Background Pancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known to promote gallstone formation.
Yukai Xiang, Xiangyu Kong, Cheng Zhang, Chuanqi He, Jingli Cai, Ruiqi Lu, Bosen Zhang, Liu Lu, Yulong Yang   +8 more
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Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

Nature Communications, 2022
Metabolic conditions associated with alterations of the gut microbiome, such as obesity and diabetes, predispose to gallstone disease. Here the authors demonstrate that the gut microbiome, in particular the genus Desulfovibrionale, contribute to ...
Hai Hu, Wentao Shao, Qian Liu, Ning Liu, Qihan Wang, Jin Xu, Xin Zhang, Zhenkun Weng, Qifan Lu, Long Jiao, Chaobo Chen, Haidong Sun, Zhaoyan Jiang, Xiaoping Zhang, Aihua Gu   +14 more
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Gallstone ileus: Unusual complication of cholelithiasis

Tungs’ Medical Journal, 2023
Gallstone ileus is an unusual complication of gallstone disease. However, gallstone ileus is a serious cause of mechanical bowel obstruction. Gallstone ileus affects older adult patients with underlying medical diseases. It occurs when a gallstone passes
Kuo-Feng Kao, Ji-Kuen Yu, Suan-Hung Yu, Chih-Wei Wei, Tai-Lin Huang   +4 more
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Gallstone Formation Follows a Different Trajectory in Bariatric Patients Compared to Nonbariatric Patients

Metabolites, 2021
Since obese patients form cholesterol gallstones very rapidly after bariatric surgery, in patients who did not form gallstones during preceding years, we hypothesized that gallstone formation follows a different trajectory in bariatric patients compared ...
Sylke Haal, Maimoena S. S. Guman, Yair I. Z. Acherman, Johannes P. G. Jansen, Michel van Weeghel, Henk van Lenthe, Eric J. M. Wever, Victor E. A. Gerdes, Rogier P. Voermans, Albert K. Groen   +9 more
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Higher visceral adiposity index was associated with an elevated prevalence of gallstones and an earlier age at first gallstone surgery in US adults: the results are based on a cross-sectional study

Frontiers in Endocrinology, 2023
ObjectiveWe sought to evaluate the association between visceral adiposity index (VAI) and the incidence of gallstones and the age at first gallstone surgery in adults in the United States.MethodsWe selected individuals from the National Health and ...
Gaopeng Zhang, Gaopeng Zhang, Zhe Ding, Zhe Ding, Junping Yang, Tianqi Wang, Li Tong, Jian Cheng, Chao Zhang   +8 more
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