Results 101 to 110 of about 102,033 (308)

Investigation of Leptin gene in broiler and layer chicken lines Investigação do gene da Leptina em linhagens de aves de corte e postura

Scientia Agricola, 2008
Leptin, a polypeptide hormone secreted mainly by adipose tissue, plays an important role in feed intake regulation, energy metabolism and reproduction in several species.
Kerli Ninov, Mônica Corrêa Ledur, Helena Javiel Alves, Millor Fernandes do Rosário, Kátia Nones, Luiz Lehmann Coutinho   +5 more
doaj   +1 more source

New host records of parasites in the Malayan red jungle fowl, Gallus gallus spadiceus [PDF]

, 1993
Thirty species of parasites were recovered from seven adult male Malayan red jungle fowls Gallus gallus spadiceus from Ulu Langat, Selangor, Malaysia. Fifteen species of the parasites are newly recorded for this host; they are Pseudolynchia canariensis ...
Babjee, Shaik Mohamed Amin, Lee, Chu Chong   +1 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Utilization of Pyrosequencing to Monitor the Microbiome Dynamics of Probiotic Treated Poultry (Gallus gallus domesticus) during Downstream Poultry Processing [PDF]

, 2017
Antibiotic growth promoters that have been historically employed to control pathogens and increase the rate of animal development for human consumption are currently banned in many countries.
Bray, Joey, Clack, Beatrice, Guttala, Vamsy Priya, Medrano, Enrique G.   +3 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes [PDF]

, 2014
This study was funded by the Sars Centre core budget to M. Adamska. Sequencing was performed at the Norwegian High Throughput Sequencing Centre funded by the Norwegian Research Council. O.M.R. and D.E.K.F.
A Saudemont, B Fahey, B Li, C Larroux, C Larroux, D Chourrout, D Darriba, DEK Ferrier, GN Luke, H-C Seo, J Garcia-Fernàndez, JF Ryan, JHL Hui, JHL Hui, KJ Peterson, M Boetzer, M Srivastava, MG Grabherr, N Takatori, O Mendivil Ramos, R Luo, S Amano, S Anders, S Fortunato, S Leininger, SA Fortunato, TM Keane, Y-F Zhong   +27 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

GAMBARAN HISTOLOGIS BURSA FABRICIUS AYAM KAMPUNG (GALLUS GALLUS DOMESTICUS) PADA UMUR BERBEDA [PDF]

, 2017
GAMBARAN HISTOLOGIS BURSA FABRICIUS AYAM KAMPUNG (Gallus gallus domesticus) PADA UMUR BERBEDAABSTRAKPenelitian ini bertujuan mengetahui gambaran histologis bursa Fabricius ayam kampung (Gallus gallus domesticus) pada umur berbeda.
Hasnita
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