Results 51 to 60 of about 25,921 (265)

Gallus gallus domesticus (Galliformes: Phasianidae) as a biological model for biosafety analysis of the hexane fraction of the fruits and seeds of Ricinus communis L. (Malpighiales: Euphorbiaciae)

Semina: Ciências Agrárias
Brazil became the largest consumer of pesticides in the world in 2021. These products, although necessary, can cause significant damage to non-target organisms and agroecosystems.
Juliana Marceli Hofma Lopes, Patricia Franchi de Freitas, Everton Ricardi Lozano, Edgar de Souza Vismara, Elizabete Artus Berté, Silvane Zancanaro de Oliveira, Camila Maria Zankanol Griebeler, Michele Potrich   +7 more
doaj   +1 more source

Evolutionary history of the mariner element galluhop in avian genomes

Mobile DNA, 2017
Background Transposable elements (TEs) are highly abundant genomic parasites in eukaryote genomes. Although several genomes have been screened for TEs, so far very limited information is available regarding avian TEs and their evolutionary histories ...
Natasha Avila Bertocchi, Fabiano Pimentel Torres, Analía del Valle Garnero, Ricardo José Gunski, Gabriel Luz Wallau   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Helminth communities in the alimentary tract of free raised chickens on rainfed and irrigated agrosystems from southwest Spain

Italian Journal of Animal Science, 2021
The helminth communities of Extremeña Azul breed chickens (Gallus gallus) have been studied from south-western free-ranging farms in Spain. Two farming systems were compared: a rainfed system and an irrigated system.
M. N. García Cuadrado, F. J. Martínez-Moreno, R. Zafra Leva, I. Acosta García   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Feasibility of Variety Chicken Businessesthe Domestic Fallandpama-Khoy In The Villagemiddle Consciousness

Agricultural Science
Cultivating gallus domestic and pama-khoy chicken varieties in Sadartengah Village is very profitable because the selling price is quite high for both gallus domesticus and pama-khoy chickens. Gallus domesticus and pama-khoy chicken varieties can be sold
Sri Purwanti, Dimas Ganda PermanaSon, Yuni Rositagoddess, ZainulArifin   +3 more
doaj   +1 more source

The complete mitochondrial genome sequence of Lindian Chicken (Gallus gallus) in China

Mitochondrial DNA. Part B. Resources, 2018
In this study, the first complete mitochondrial genome of Lindian Chicken (Gallus gallus) was sequenced in order to develop the mitogenome data for genus gallus.
Yuan Xu, Enze Jiang, Chong Chen, Jiayu Liu, Keli Zhu, Zhen Zhang, Fangyong Ning, Zhiheng Du, Xiujuan Bai   +8 more
doaj   +1 more source

A New Chicken Genome Assembly Provides Insight into Avian Genome Structure

G3: Genes, Genomes, Genetics, 2017
The importance of the Gallus gallus (chicken) as a model organism and agricultural animal merits a continuation of sequence assembly improvement efforts.
Wesley C. Warren, LaDeana W. Hillier, Chad Tomlinson, Patrick Minx, Milinn Kremitzki, Tina Graves, Chris Markovic, Nathan Bouk, Kim D. Pruitt, Francoise Thibaud-Nissen, Valerie Schneider, Tamer A. Mansour, C. Titus Brown, Aleksey Zimin, Rachel Hawken, Mitch Abrahamsen, Alexis B. Pyrkosz, Mireille Morisson, Valerie Fillon, Alain Vignal, William Chow, Kerstin Howe, Janet E. Fulton, Marcia M. Miller, Peter Lovell, Claudio V. Mello, Morgan Wirthlin, Andrew S. Mason, Richard Kuo, David W. Burt, Jerry B. Dodgson, Hans H. Cheng   +31 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source