Results 61 to 70 of about 5,752 (150)

Characterization of a novel exonic deletion in the GALNS gene causing Morquio A syndrome

Molecular Genetics and Metabolism Reports, 2022
Mucopolysaccharidosis IVA or Morquio A syndrome is a rare lysosomal storage disorder caused by N-acetylgalactosamine-6-sulfatase deficiency. A diagnosis can be provided by the identification of reduced N-acetylgalactosamine-6-sulfatase activity as well ...
Kathryn DeLong, Annette Feigenbaum, Laura Pollard, Andrew Lay, Timothy Wood   +4 more
doaj   +1 more source

Low‐Molecular‐Weight Angelica sinensis Polysaccharide Improves Neurological Function and Neuroplasticity Following Cerebral Ischemia–Reperfusion Injury

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Low‐molecular‐weight Angelica sinensis polysaccharide was extracted, and its characteristics were determined via chromatography and spectroscopy. Our findings demonstrate that LMW‐ASP effectively improves neurological function and neuroplasticity following cerebral ischemia‐reperfusion injury.
Junbin Lin, Ting Jiang, Xin Zhang, Lu Xia, Yu Gong, Weijing Liao   +5 more
wiley   +1 more source

Decoupling control synthesis for an oblique-wing aircraft [PDF]

Interest in oblique-wing aircraft has surfaced periodically since the 1940's. This concept offers some substantial aerodynamic performance advantages but also has significant aerodynamic and inertial cross-coupling between the aircraft longitudinal and ...
Alag, G. S., Kempel, R. W., Pahle, J. W.
core   +2 more sources

Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA [PDF]

, 2014
Mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities, is caused by an inherited deficiency of the enzyme N-sulfoglucosamine sulfohydrolase (SGSH ...
Becker, Stefan, Gärtner, Jutta, Krätzner, Ralph, Pröpper, Kevin, Schreiber, Kathrin, Sheldrick, George M., Sidhu, Navdeep S., Steinfeld, Robert, Usón, Isabel   +8 more
core   +2 more sources

A 9-Month-Old with Skeletal Abnormalities and a Consanguineous Sibling with Mucopolysaccharidosis IVA: The Role of Urinary Glycosaminoglycan Testing in Disease Diagnosis and Treatment Monitoring

Clinical Medicine Insights: Case Reports, 2021
Mucopolysaccharidosis IVA (MPS IVA) is a rare autosomal recessive lysosomal storage disorder resulting from N-acetylgalactosamine-6-sulfatase (GALNS) deficiency that occurs in approximately 1 in 76 000 to 1 in 640 000 live births.
Eric Goldman, Angela Vu, Kelly Dietz, Stefani N Thomas   +3 more
doaj   +1 more source

SynCom‐mediated herbicide degradation activates microbial carbon metabolism in soils

iMeta, Volume 4, Issue 5, October 2025.
Extensive herbicide residues in the black soil of northeastern China are considered a significant agricultural pollution threat, yet effective bioremediation of this complex and persistent mixture remains a challenge. We provided an herbicide degradation and ecosystem regulation model of SynCom in soil. We also demonstrated the effectiveness of SynCom “
Yuxiao Zhang, Jack A. Gilbert, Xuan Liu, Li Nie, Xiyuan Xu, Guifeng Gao, Lihui Lyu, Yuying Ma, Kunkun Fan, Teng Yang, Yumeng Zhang, Jiabao Zhang, Haiyan Chu   +12 more
wiley   +1 more source

Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli

ChemBioChem, Volume 26, Issue 17, September 15, 2025.
This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa, Shane M. Coyle, Fiona Walsh, Trinidad Velasco‐Torrijos   +3 more
wiley   +1 more source

Mangrove restoration enhances blue carbon sequestration and its stability in a subtropical tidal wetland

Functional Ecology, Volume 39, Issue 9, Page 2437-2451, September 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Mangrove forests are among the most productive blue carbon (C) ecosystems. While mangrove restoration is recognized for its potential to increase coastal blue C storage, its effects on soil organic C (SOC) stability and sources remain poorly understood.
Xingyun Huang, Wensui Li, Guoming Qin, Fangyuan Guan, Yongxing Cui, Jingwei Shi, Zhe Lu, Lulu Zhang, Jingfan Zhang, Jinge Zhou, Ruyi Ding, Hua He, Evans Asenso, Hui Li, Faming Wang   +14 more
wiley   +1 more source

Uso de vectores derivados de virus adenoasociados para el tratamiento de la enfermedad de Morquio A

Revista Universitas Medica, 2009
En el desarrollo de una estrategia de terapia génica para la mucopolisacaridosis IV A (enfermedad de Morquio A), en el presente trabajo se evaluó la capacidad de un vector adenoasociado (AAV) para expresar el gen de la enzima sulfatasa N ...
CARLOS JAVIER ALMÉCIGA-DÍAZ, MARÍA ANDREA RUEDA-PÁRAMO, OLGA YANETH ECHEVERRI, ADRIANA MARÍA MONTAÑO, SHUNJI TOMATSU, LUIS ALEJANDRO BARRERA   +5 more
doaj  

Generation of a cellular model for mucopolysaccharidosis type IVA (MPS IVA) (AOUMEYi003-A) from a patient carrying compound heterozygous mutations p.G116V and p.G290S in the GALNS gene

Stem Cell Research
Mucopolysaccharidosis type IVA (MPS IVA) is an autosomal recessive lysosomal storage disorder (LSD) caused by a deficiency of enzyme N-acetylgalactosamine-6-sulfatase (GALNS), characterised by systemic skeletal dysplasia and joint abnormalities with ...
Federica Feo, Silvia Falliano, Anna Caciotti, Marina Rinaldi, Alessia Caroli, Laura Giunti, Martino Calamai, Elena Procopio, Renzo Guerrini, Amelia Morrone, Rodolfo Tonin   +10 more
doaj   +1 more source