Results 51 to 60 of about 799,270 (269)

Progression along the invasion curve: silver carp growth slows temporally in two Missouri River tributaries [PDF]

open access: yesAquatic Invasions
Silver carp (Hypophthalmichthys molitrix Valenciennes, 1844) have been invading North American rivers for decades, often altering zooplankton community structure and impacting native fishes.
Justin D. Harms   +5 more
doaj   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Minkowski Games [PDF]

open access: yesACM Transactions on Computational Logic, 2018
We introduce and study Minkowski games. These are two-player games, where the players take turns to choose positions in R<sup<d</sup< based on some rules. Variants include boundedness games, where one player wants to keep the positions bounded, and the other wants to escape to infinity; as well as safety games, where one player wants to ...
Stéphane Le Roux 0001   +2 more
openaire   +9 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Heavy metal accumulation by willow clones in short-time hydroponics

open access: yesJournal of Forest Science, 2010
: The differences in Pb and Cd accumulation capabilities of Salix miyabeana, S. viminalis, S. × blanda, and S. elbursensis derived from willows planted in 1997 in coal-ash settling localities in the Krušné hory Mts.,the Czech Republic, were determined ...
J. Malá   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Integrating ASCAT surface soil moisture and GEOV1 leaf area index into the SURFEX modelling platform: a land data assimilation application over France [PDF]

open access: yesHydrology and Earth System Sciences, 2014
The land monitoring service of the European Copernicus programme has developed a set of satellite-based biogeophysical products, including surface soil moisture (SSM) and leaf area index (LAI).
A. L. Barbu   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

El Juego como Estrategia Didáctica para el fortalecimiento de los valores morales en los niños y niñas de 8 a 9 años de Educación Básica

open access: yesCiencia UNEMI, 2015
In this detailed research work, field and cross are disclosed whose objective was to establish whether the game is present as a teaching strategy in both the school and family context, children from 8-9 years of primary education, of the Education Unit ...
Game-Mendoza, Karla
doaj  

Evaluation of root water uptake in the ISBA-A-gs land surface model using agricultural yield statistics over France [PDF]

open access: yesHydrology and Earth System Sciences, 2014
The simulation of root water uptake in land surface models is affected by large uncertainties. The difficulty in mapping soil depth and in describing the capacity of plants to develop a rooting system is a major obstacle to the simulation of the ...
N. Canal   +5 more
doaj   +1 more source

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