Results 41 to 50 of about 221,034 (264)
ACM Transactions on Computational Logic, 2018 We introduce and study Minkowski games. These are two-player games, where the players take turns to choose positions in R<sup<d</sup< based on some rules. Variants include boundedness games, where one player wants to keep the positions bounded, and the other wants to escape to infinity; as well as safety games, where one player wants to ...
Stéphane Le Roux 0001 +2 more
openaire +9 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Heavy metal accumulation by willow clones in short-time hydroponics
Journal of Forest Science, 2010 : The differences in Pb and Cd accumulation capabilities of Salix miyabeana, S. viminalis, S. × blanda, and S. elbursensis derived from willows planted in 1997 in coal-ash settling localities in the Krušné hory Mts.,the Czech Republic, were determined ...
J. Malá +4 more
doaj +1 more source
Integrating ASCAT surface soil moisture and GEOV1 leaf area index into the SURFEX modelling platform: a land data assimilation application over France [PDF]
Hydrology and Earth System Sciences, 2014 The land monitoring service of the European Copernicus programme has developed a set of satellite-based biogeophysical products, including surface soil moisture (SSM) and leaf area index (LAI).
A. L. Barbu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Ciencia UNEMI, 2015 In this detailed research work, field and cross are disclosed whose objective was to establish whether the game is present as a teaching strategy in both the school and family context, children from 8-9 years of primary education, of the Education Unit ...
Game-Mendoza, Karla
doaj
Evaluation of root water uptake in the ISBA-A-gs land surface model using agricultural yield statistics over France [PDF]
Hydrology and Earth System Sciences, 2014 The simulation of root water uptake in land surface models is affected by large uncertainties. The difficulty in mapping soil depth and in describing the capacity of plants to develop a rooting system is a major obstacle to the simulation of the ...
N. Canal +5 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Playing Games with Timed Games [PDF]
IFAC Proceedings Volumes, 2009 In this paper we focus on property-preserving preorders between timed game automata and their application to control of partially observable systems. Following the example of timed simulation between timed automata, we define timed alternating simulation as a preorder between timed game automata, which preserves controllability.
Chatain, Thomas +2 more
openaire +3 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source