Results 71 to 80 of about 3,284,655 (301)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Disco Polo from the Podhale Region: The Cultural Power Game [PDF]

, 2020
Maria Małanicz-Przybylska
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Human-Bear Conflicts in Massanutten Village: Achieving Success Requires Partnerships

Human-Wildlife Interactions, 2018
Interactions between humans and black bears (Ursus americanus) in Virginia, USA, increase as bear populations recover from historically low levels and expand their range to seek food in human-modified environments.
Ally M. Scott, David M. Kocka, Glenn W. Mitchell   +2 more
doaj   +1 more source

Extensibility and limitations of FDDI [PDF]

Recently two standards for Metropolitan Area Networks (MANs), Fiber Distributed Data Interface (FDDI) and Distributed Queue Dual Bus (DQDB), have emerged as the primary competitors for the MAN arena.
Game, David, Maly, Kurt J.
core   +1 more source

Game Harmony: A Short Note [PDF]

, 2000
Strategic uncertainty in game theory may have two different general sources, either alone or in combination: uncertainty because of the existence of a coordination problem, and uncertainty because of a conflict between one own and the other n players ...
Zizzo, Daniel John
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Morphohistological Structure of Liver in Wild Deer (Cervidae) as Indicator of Population Well-Being

Техника и технология пищевых производств
Wild ungulates are a convenient object for environmental monitoring. The authors used the histological structures in deer’s liver to assess the well-being of populations in unfavorable anthropogenic and natural habitats.
Maria A. Perevozchikova, Iraida I. Okulova, Alexey A. Sergeyev, Igor A. Domsky, Valeriy V. Shiryaev, Mikhail G. Dvornikov, Boris E. Zarubin   +6 more
doaj   +1 more source

Performance of gigabit FDDI [PDF]

Great interest exists in developing high speed protocols which will be able to support data rates at gigabit speeds. Hardware currently exists which can experimentally transmit at data rates exceeding a gigabit per second, but it is not clear as to what ...
Game, David, Maly, Kurt J.
core   +1 more source