Results 111 to 120 of about 831,519 (303)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Language Functions Used by the Main Character in Sherlock Holmes II: a Game of Shadows Movie [PDF]

open access: yes, 2014
This research focused on language functions used by the main character in “Sherlock Holmes” movie. The aims were to find the use of language functions and describe the dominant types of language functions used in “Sherlock Holmes” movie.
Arista, S. D. (Sri), Murni, S. M. (Sri)
core  

Character Based Rhythm Game Design

open access: yes, 2023
Nowadays, we've got tons of rhythm games to choose from. Some focus on music and gameplay, while others are centered around characters. But here's the thing: none of them let players control character abilities. Usually, those abilities are automated and kick in once you hit a certain goal, regardless of where you are in the song or how tough it is. In
openaire   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

A kinect game in the VirtualSign project: training and learning with gestures [PDF]

open access: yes, 2015
Comunicação apresentada na 7ª Conferência Internacional de Arte Digital realizada em Óbidos de 19-20 de março de 2015This paper presents the development of a game aimed at making the process of learning sign language enjoyable and interactive, using the ...
Baltazar, Ana Bela   +8 more
core   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

GAME PEMBELAJARAN ANGKA DAN HURUF HIJAIYAH BERBASIS J2ME [PDF]

open access: yes, 2010
The growth of education game being based on J2Me which progressively make all game developer compete to create the education game especially for children. However,education game owning value islami felt still less.
Avianto, Nurrahmad   +2 more
core  

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio   +8 more
wiley   +1 more source

Young People Speculating with and About Hope Through a Life-Friendly Cli-Fi Roleplaying Game: Disrupting Environmental and Sustainability Education/Research

open access: yesAustralian Journal of Environmental Education
The signals and consequences of, and currently overall eco-socio-cultural inadequate responses to, the pressing climate and biodiversity crises of the Anthropocene foster a landscape of repression, hopelessness and anxiety among many, not least young ...
Michael Paulsen   +3 more
doaj   +1 more source

Player identification in American McGee’s Alice : a comparative perspective [PDF]

open access: yes, 2008
In this paper I analyse personal identification in three incarnations of Alice in Wonderland: the original novels, the 1950s Disney animation film and the computer game American McGee’s Alice.
Van Looy, Jan
core  

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