Results 51 to 60 of about 114,049 (263)
Applied SciencesMisconceptions about sound are common among primary-school pupils, but research on voice-interactive game-based learning remains limited, especially regarding the role of scaffolding. We investigated whether a voice-interactive 2D platformer with a three-
Minyu Che +4 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Ecology and Evolution, 2020 Glacier bears are a rare grey color morph of American black bear (Ursus americanus) found only in northern Southeast Alaska and a small portion of western Canada.
Tania Lewis +4 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Experimenting With a Digital Application to Codesign Ikat Textile Patterns With Weaving Community
Human Behavior and Emerging TechnologiesThis article presents a multidisciplinary research project that involves a digital application developed for ikat weaving communities from Chonnabot District in Khon Kaen Province in Thailand.
Warin Boonyaputthipong +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Nirmana, 2012 Sejarah Jakarta terbentang mulai dari abad ke-4 Masehi, mengalami perkembangan pesat pada masa pemerintahan Belanda antara abad ke-17 hingga 19 Masehi, dan mewarisi Republik Indonesia dengan peninggalan-peninggalan infrastruktur serta kultural di kota ...
Sigit Adinugroho, Intan Rizky Mutiaz
doaj
CoRR, 2019 "Theorem proving is similar to the game of Go. So, we can probably improve our provers using deep learning, like DeepMind built the super-human computer Go program, AlphaGo." Such optimism has been observed among participants of AITP2017. But is theorem proving really similar to Go?
openaire +2 more sources
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source