Results 41 to 50 of about 1,414,699 (298)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A Hexagon Sensor and A Layer-Based Conversion Method for Hexagon Clusters

Information
In reinforcement learning (RL), precise observations are crucial for agents to learn the optimal policy from their environment. While Unity ML-Agents offers various sensor components for automatically adjusting the observations, it does not support ...
Jun-Ho Kim, Hanul Sung
doaj   +1 more source

Wearable Sensors for Vital Signs Measurement: A Survey

Journal of Sensor and Actuator Networks, 2022
With the outbreak of coronavirus disease-2019 (COVID-19) worldwide, developments in the medical field have aroused concerns within society. As science and technology develop, wearable medical sensors have become the main means of medical data acquisition.
Zhihan Lv, Yuxi Li
doaj   +1 more source

Designing multiplayer games to facilitate emergent social behaviours online [PDF]

, 2005
This paper discusses an exploratory case study of the design of games that facilitate spontaneous social interaction and group behaviours among distributed individuals, based largely on symbolic presence 'state' changes. We present the principles guiding
Allen C., Biocca F., Christiansen N., Dodge M. A., Freeman L., Garneau P-A, Halverson C., Holldobler B., Johnson S., Lombard M., Manninen T., Marc Eisenstadt, NASA, Opie I., Rheingold H., Scott P., Vogiazou Y., Vogiazou Y., Vogiazou Y., Wolfram S., Yanna Vogiazou   +20 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Let the Body’n’Brain Games Begin: Toward Innovative Training Approaches in eSports Athletes

Frontiers in Psychology, 2020
The phenomenon of eSports is omnipresent today. International championships and their competitive athletes thrill millions of spectators who watch as eSports athletes and their teams try to improve and outperform each other.
Anna Lisa Martin-Niedecken, Alexandra Schättin   +1 more
doaj   +1 more source

A Sentiment Analysis of Turkish Tweets Shared in Nursing Week During the Pandemic

Sağlık ve Hemşirelik Yönetimi Dergisi, 2022
Aim: This study aimed to conduct an artificial intelligence-based sentiment analysis of Turkish tweets about nursing during the nursing week during the COVID-19 pandemic. Method: This is a retrospective descriptive survey. Between May 4 and May 19, 2021,
Muzaffer Berna Doğan, Volkan Oban, Gül Dikeç   +2 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Terms of Service: Coming to Terms with AI-Generated Art in the Classroom’ [PDF]

Athens Journal of Humanities & Arts
This paper describes the plan and design of a new course, entitled “AI & Art.” The course introduces select tools made possible by generative artificial intelligence and large language models (LLMs).
Gregory P. Garvey
doaj   +1 more source

Assessing the role of conceptual knowledge in an anti-phishing game [PDF]

, 2014
Copyright @ 2014 IEEE. This is the author accepted version of this article.Games can be used to support learning and confidence development in several domains, including the secure use of computers.
Arachchilage, NAG, Ghinea, G, Scott, MJ
core   +1 more source