Results 41 to 50 of about 886,236 (299)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
SAGE Open, 2021 This article aims to capitalize on game theoretic techniques for optimal service marketing decision based on existing literature review. The study collated relevant literature and reviewed the relationship that exists between game theory and marketing ...
Oluwakemi T. Oreagba +2 more
doaj +1 more source
There Is No Immersion: Critical Intervention through Hypermediacy in Metagames
Eludamos, 2021 In 2020, Draw Me a Pixel released There Is No Game, a game that playfully engages with the concept of the metagame and its varied meanings to examine the relationship between developers, games, and their audiences. The game has much in common with other
Sarah Thorne
doaj +1 more source
Modelling Early User-Game Interactions for Joint Estimation of Survival Time and Churn Probability
, 2019 Data-driven approaches which aim to identify and predict player engagement are becoming increasingly popular in games industry contexts. This is due to the growing practice of tracking and storing large volumes of in-game telemetries coupled with a ...
Bonometti, Valerio +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Научный диалог, 2019 The specifics of the historical development of the Japanese gaming industry are considered. A periodization of the history of the gaming industry in Japan is proposed, a description of its main stages is presented: the emergence in the 1970s, access to ...
G. N. Valiakhmetova, G. N. Bilobrova
doaj +1 more source
Towards a Lightweight Approach for Modding Serious Educational Games: Assisting Novice Designers [PDF]
, 2014 Serious educational games (SEGs) are a growing segment of the education community’s pedagogical toolbox. Effectively creating such games remains challenging, as teachers and industry trainers are content experts; typically they are not game designers ...
Brylow, Dennis +5 more
core +1 more source
Advanced Engineering Materials, EarlyView.Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
Gaming as a potential source of conflict with real life: The youth’s assessments
RUDN journal of SociologyToday, gaming practices seem to be at the forefront of the formation of a future society. In the current era of global digital transformations, the moment of total public involvement in the new digital reality was recorded in 2016, when an augmented ...
A. K. Mamedov +3 more
doaj +1 more source
Customer Involvement in the Game Development Process
Journal of Entrepreneurship, Management and Innovation, 2015 The creative industry is a fast developing sector of economy in many countries. Growing competition in this area has led many companies to implement strategy of users' involvement in product development in order to deliver products that are more aligned ...
Kaja Prystupa-Rządca, Justyna Starostka
doaj +1 more source