Results 81 to 90 of about 886,236 (299)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

The Economic Effect of Competition in the Air Transportation Industry [PDF]

open access: yes, 1972
The air transportation industry has been described as a highly-competitive, regulated oligopoly or as a price-regulated cartel with blocked entry, resulting in excessive service and low load factors.
Hubbard, H. B.
core   +1 more source

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

open access: yesAdvanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou   +17 more
wiley   +1 more source

Investment Optimal Portfolio as an Answer for Human Needs and Current Trends

open access: yesEastern European Journal of Transnational Relations
This study examines the influence of digital transformation on human activity and its implications for investment decision-making during the COVID-19 pandemic.
Ihor Hurnyak, Oleksandra Werbowa
doaj   +1 more source

Ceramic Particle‐Reinforced Medium‐Entropy Alloys With Outstanding Mechanical Properties Prepared by Novel Micro‐LPBF

open access: yesAdvanced Functional Materials, EarlyView.
An innovative medium entropy alloy (MEA) composite material was fabricated via micro laser powder bed fusion (μ‐LPBF) with appropriate nano‐ceramic particles doping and exhibited markedly improved overall performance, including synergistically enhanced strength and ductility, increased hardness and compressive strength, improved wear resistance and ...
Zhonglin Shen, Mingwang Fu
wiley   +1 more source

The sustainable cooperative tariffs : a political economy perspective [PDF]

open access: yes
The purpose of this paper is to examine the international trade cooperation in order to determine the sustainable cooperative tariff rates in a political economy perspective. This paper establishes a tariff-setting game among two countries as a two-phase
Racem Mehdi
core  

The Effects of Video Games on Human Intelligence [PDF]

open access: yes, 2018
With the help of rapidly growing electronics industry offering more affordable electronic gaming devices, an increasing number of people have stepped into the realm of video games and as a result, playing video games has become part of life for many to ...
Hu, Wenxiang, Yuan, Lifeng
core   +1 more source

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

open access: yesAdvanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu   +7 more
wiley   +1 more source

Through Diamond Robust Surface Enhanced Raman Spectroscopy

open access: yesAdvanced Functional Materials, EarlyView.
Thin film diamond growth offers a unique opportunity for Surface Enhanced Raman Spectroscopy (SERS); the encapsulation of plasmonic nanostructures within a transparent, chemically stable, and physically robust coating. The diamond acts as both a window and protective layer, enabling illumination of the plasmonic nanostructures through the diamond ...
Kieran N. Twaddle   +4 more
wiley   +1 more source

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