Results 41 to 50 of about 956,602 (281)

Competitive facility location: the Voronoi game

open access: yesTheoretical Computer Science, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ahn, HK   +4 more
openaire   +6 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Thinking Through the Box: Evaluating a 3D Game to Engage Penetrative Thinking

open access: yesFrontiers in Virtual Reality, 2020
Spatial skills allow us to mentally imagine and manipulate objects and their spatial relations. These skills are crucial in both every day and expert tasks.
Aarohi Pathak   +7 more
doaj   +1 more source

Shapley Facility Location Games [PDF]

open access: yes, 2017
Facility location games have been a topic of major interest in economics, operations research and computer science, starting from the seminal work by Hotelling. Spatial facility location models have successfully predicted the outcome of competition in a variety of scenarios.
Ben-Porat, Omer, Tennenholtz, Moshe
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Development and Usability of a Location-based Game.

open access: yesInteraction Design and Architecture(s)
Location-based games (LBG) incorporate players’ location as their main game element. Therefore, they are played in the physical world by turning every place into a playground. Due to the pervasive nature of LBGs, usability evaluation can differ from
Faraz Badali Naghadeh, Kursat Cagiltay
doaj   +1 more source

A Game-Theoretic Framework to Preserve Location Information Privacy in Location-Based Service Applications

open access: yesSensors, 2019
Recently, the growing ubiquity of location-based service (LBS) technology has increased the likelihood of users’ privacy breaches due to the exposure of their real-life information to untrusted third parties.
Mulugeta Kassaw Tefera, Xiaolong Yang
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

The Sequential Hotelling Game with One Parameterized Location

open access: yesAppliedMath
This article studies the location–price Hotelling game. Numerous studies have been conducted on the Hotelling game with simultaneous decisions; however, in real-life scenarios, decisions are frequently sequential. Unfortunately, studies on the sequential
Luis Garcia-Perez   +3 more
doaj   +1 more source

Optimization on cooperative government and enterprise supplies repertories for maritime emergency: A study case in China

open access: yesAdvances in Mechanical Engineering, 2019
This article studies the location problem of maritime emergency supplies repertories under the joint of government and enterprises, and it proposes the two-stage optimization location model by integrating the location of maritime emergency supplies ...
Yunfei Ai, Qi Zhang
doaj   +1 more source

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