Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu +8 more
wiley +1 more source
The Impact Mechanism of Government Regulation on the Operation of Smart Health Senior Care Service Platform: A Perspective From Evolutionary Game Theory. [PDF]
Xiao M, Liu H.
europepmc +1 more source
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li +9 more
wiley +1 more source
Game theory elucidates how competitive dynamics mediate animal social networks. [PDF]
Dubois F.
europepmc +1 more source
Interfacial Synergy in a Band‐Aligned Low‐Dimensional Heterojunction Toward Broadband Photodetection
Monolithically integrating sensing and communication, a Ta2NiSe5/Sb2Te3 heterojunction achieves visible‐to‐near‐infrared photovoltaics with high‐speed terahertz photo‐thermoelectric detection at room temperature. By engineering a Type‐II van der Waals heterojunction, we overcome the intrinsic spectral limitations and disparate physical requirements of ...
Yuanfeng Wen +20 more
wiley +1 more source
Double layers optimal scheduling of distribution networks and photovoltaic charging and storage station cluster based on leader follower game theory. [PDF]
Liu Z, Wu J, Zhu R, Kong D, Guo H.
europepmc +1 more source
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
The susceptibility assessment of debris flow hazards based on the game theory combination weighting-normal cloud model. [PDF]
Yang XT, Gu XB.
europepmc +1 more source
Energy and throughput aware adequate routing for wireless sensor networks using integrated game theory method. [PDF]
Vivek Kumar M, Saraniya O.
europepmc +1 more source
Research on regenerative braking control of electric vehicles based on game theory optimization. [PDF]
Li C, Zhang L, Lian S, Liu M.
europepmc +1 more source

