Results 51 to 60 of about 85,893 (311)

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

A Dynamic Network Model of Societal Complexity and Resilience Inspired by Tainter’s Theory of Collapse

Entropy
In recent years, several global events have severely disrupted economies and social structures, undermining confidence in the resilience of modern societies.
Florian Schunck, Marc Wiedermann, Jobst Heitzig, Jonathan F. Donges   +3 more
doaj   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

The fiducial lower confidence limits of reliability for standby system based on zero-failure data(基于无失效数据贮备系统可靠性的fiducial置信限)

Zhejiang Daxue xuebao. Lixue ban, 2010
研究元件具有无失效试验数据的贮备系统可靠性的评定问题.由无失效试验数据下元件可靠性置信下限的定义,得到元件分布参数的fiducial分布.并以此为出发点,对基于指数寿命型元件的无失效成败型试验数据、贮备系统的切换开关的成败型试验数据,在开关的成功概率分别为已知和未知的情形下,导出了由指数寿命型元件组成的贮备系统可靠性的fiducial置信下限的计算公式,并给出了算例.
JIANGRen-bin(蒋仁斌), JIANGDian-yu(姜殿玉)   +1 more
doaj   +1 more source

Game Theory and Game Mechanics Design [PDF]

SHS Web of Conferences
This paper focuses on the significance of game balance in games and explores the application of game theory concepts for designing and analyzing balanced gameplay.
Pi Jiasheng
doaj   +1 more source

Game Theory and Emotions [PDF]

Rationality and Society, 1997
To illustrate the rational-choice modeling of emotions, a game-theoretic model of frustration, in which players respond in anger to their lack of control, is developed. Of the 57 distinct 2 × 2 strict ordinal conflict games, 12 turn out to be `frustration games', in four of which `threat power', based on the theory of moves, offers relief to the ...
openaire   +3 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Application of Game Theory in Integrated Energy System Systems: A Review

IEEE Access, 2020
With the rapid development of society, global energy is in short supply. China has put forward an integrated energy system focusing on interconnecting energy resources and harnessing their complementary advantages to address the energy crisis, thus no ...
Jun He, Yi Li, Huangqiang Li, Huamin Tong, Zhijun Yuan, Xiaoling Yang, Wentao Huang   +6 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Game Theory and Literature [PDF]

Games and Economic Behavior, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources