Results 51 to 60 of about 1,377,749 (341)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Game Theory and Literature [PDF]
Games and Economic Behavior, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Does game theory work? The bargaining challenge [PDF]
, 2007 Book description: This volume brings together all of Ken Binmore's influential experimental papers on bargaining along with newly written commentary in which Binmore discusses the underlying game theory and addresses the criticism leveled at it by ...
Binmore, K.G.
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Cooperative quantum Parrondo's games
, 2013 Coordination and cooperation are among the most important issues of game theory. Recently, the attention turned to game theory on graphs and social networks.
Pawela, Łukasz, Sładkowski, Jan
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
EntropyIn recent years, several global events have severely disrupted economies and social structures, undermining confidence in the resilience of modern societies.
Florian Schunck +3 more
doaj +1 more source
Giffen paradoxes in quantum market games
, 2002 Recent development in quantum computation and quantum information theory allows to extend the scope of game theory for the quantum world. The paper presents the history and basic ideas of quantum game theory.
Bednarek +15 more
core +1 more source