Results 111 to 120 of about 93,041 (352)

Preserved Function of Afferent Parvalbumin-Positive Perisomatic Inhibitory Synapses of Dentate Granule Cells in Rapidly Kindled Mice

open access: yesFrontiers in Cellular Neuroscience, 2018
Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory ...
Marita G. Hansen   +4 more
doaj   +1 more source

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

open access: yes, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +1 more source

Correlations of Amino Acids with Secondary Structure Types: Connection with Amino Acid Structure [PDF]

open access: yesarXiv, 2005
The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25.
arxiv  

Changes in Descending Pain Modulation During Anti–Tumor Necrosis Factor Therapy: A Prospective Study in Rheumatoid Arthritis and Spondyloarthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective In rheumatoid arthritis (RA) and spondyloarthritis (SpA), managing persistent pain remains challenging. Little is known regarding impaired pain pathways in these patients and the impact of biologic disease‐modifying antirheumatic drugs (bDMARDs).
Anne‐Priscille Trouvin   +9 more
wiley   +1 more source

Linking chronic stress to insomnia symptoms in older adults: The role of stress co‐occurrence during the pandemic

open access: yesResearch in Nursing &Health, Volume 46, Issue 1, Page 68-79, February 2023., 2023
Abstract Studies examining the associations of chronic stressors with sleep health in older adults have shown conflicting results. While the COVID‐19 pandemic increased perceived stress at the population level, less is known about chronic stressors experienced by older adults in the context of the COVID‐19 pandemic and its impact on sleep health in an ...
Wan‐Chin Kuo   +4 more
wiley   +1 more source

Detection of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in Dicrocoelium dendriticum

open access: yesParasite, 2000
In the present study we report the presence of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in crude extracts of Dicrocoelium dendriticum. This indirectly demonstrates the presence of acetylcholine and GABA.
Giménez-Pardo C.   +3 more
doaj   +1 more source

Allosteric modulation of retinal GABA receptors by ascorbic acid [PDF]

open access: yes, 2011
Ionotropic GABA receptors (GABAA and GABAC) belong to the Cys-loop receptor family of ligand-gated ion channels. GABAC receptors are highly expressed in the retina, mainly localized at the axon terminals of bipolar cells.
Aguayo, Luis G.   +5 more
core   +1 more source

Trends in gabapentinoid prescribing: A nationwide Danish drug utilization study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pregabalin and gabapentin are increasingly used for pain and other conditions. Concerns exist about overuse as well as potential misuse and abuse. To guide rational prescribing practices, we provide detailed nationwide data on the use of gabapentinoids in Denmark.
Anton Pottegård   +7 more
wiley   +1 more source

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity

open access: yesCell Reports, 2018
Summary: Brown adipose tissue (BAT) is a metabolically active organ that contributes to the maintenance of systemic metabolism. The sympathetic nervous system plays important roles in the homeostasis of BAT and promotes its browning and activation ...
Ryutaro Ikegami   +16 more
doaj  

Dysregulation of visual motion inhibition in major depression [PDF]

open access: yes, 2016
Individuals with depression show depleted concentrations of the inhibitory neurotransmitter GABA in occipital (visual) cortex, predicting weakened inhibition within their visual systems.
Chen, Yue   +4 more
core   +1 more source

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