Results 121 to 130 of about 93,041 (352)

Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]

arXiv, 2006
Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv  

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

INHIBITORY NEUROTRANSMITTERS AND THEIR INFLUENCE ON TUMOR IN PATIENTS WITH GLIOMAS

Сибирский онкологический журнал, 2016
The review deals with the problem of activity of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter, in gliomas. It has been shown that GABA has an antitumor activity in most models and cancer patients have an increased level of GABA ...
A. V. Kartashev, V. B. Voitenkov
doaj  

Enhancement of Antioxidant Activity and Bioactive Compounds in Soy Whey Fermented with Lactiplantibacillus plantarum and Weissella confusa [PDF]

مجله پژوهش‌های علوم و صنایع غذایی ایران
Soy whey (SW) is a byproduct from tofu and soy protein isolate (SPI) production that contains various nutrients such as protein, amino acids, minerals, carbohydrates, isoflavones.
Shadi Atashgahi, Ali Moayedi, Alireza Sadeghi Mahoonak, Hoda Shahiri Tabarestani, Alireza Sadeghi   +4 more
doaj   +1 more source

Genetic Code Table: A note on the three splittings into amino acid classes [PDF]

arXiv, 2009
This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their complements, and 6 non-complements) are observed now together with two further possible splittings into 4 x 5 and 5 x ...
arxiv  

Highly‐Selective Electrochemical Decarboxylative Late‐Stage Functionalization of Amino Acids

Chemistry – A European Journal, EarlyView.
Electrochemical decarboxylative late‐stage functionalization of the C‐ or N‐terminus of natural amino acids is presented. Metal and catalyst‐free protocol widely explored the synthesis of hindered ethers, amines, or di‐peptide. Abstract A unified electrochemical decarboxylative strategy for the site‐selective construction of carbon‐heteroatom bonds is ...
Adrija Ghosh, Vishal Kumar Parida, Tristan von Münchow, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +1 more source

Quality marker prediction in Trillium tschonoskii based on UHPLC–MS chemical characterisation and network pharmacology

Phytochemical Analysis, Volume 34, Issue 1, Page 76-91, January 2023., 2023
Abstract Introduction As a folk herbal medicine, Trillium tschonoskii has been used for thousands of years. However, due to the complexity of the chemical constituents of this herb, few investigations have acquired a comprehensive understanding of its quality markers.
Zhixin Wang, Rao Fu, Na Zhu, Junqi Wang, Xiaorui Zhang, Xiulan Huang, Zhiyong Li   +6 more
wiley   +1 more source

Effect of Curcumin on the Hypothalamus Levels of the Potent Inhibitory Neurotransmitter ,Gamma aminobutyric acid

Research in Molecular Medicine, 2015
Background: There are some reports in the literature showing that hypothalamus synthesizes and secretes amino acid neurotransmitters. According to several studies, elevated serum levels of gamma-amino butyric acid (GABA), a potent inhibitory ...
Shokoufe Nikpour Moghaddam, Durdi Qujeq, Ali Asghar Rastegari Efahani, Shaghayeq Nikpour Moghaddam   +3 more
doaj  

Potentiation of gamma aminobutyric acid receptors (GABAAR) by Ethanol: How are inhibitory receptors affected?

Frontiers in Cellular Neuroscience, 2016
In recent years there has been an increase in the understanding of ethanol actions on the type A -aminobutyric acid chloride channel (GABAAR), a member of the pentameric ligand gated ion channels (pLGICs).
Benjamin eFörstera, P A Castro, Gustavo eMoraga-Cid, Luis Gerardo Aguayo   +3 more
doaj   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

Clinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund, Annette Haerdtlein, Wolfgang Fehrmann, Clara Weglage, Tobias Dreischulte, Ulrich Jaehde   +5 more
wiley   +1 more source