Results 91 to 100 of about 17,829 (311)

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

Probing Thermal Electrons in Gamma-Ray Burst Afterglows

The Astrophysical Journal
Particle-in-cell simulations have unveiled that shock-accelerated electrons do not follow a pure power-law distribution, but have an additional low-energy “thermal” part, which owns a considerable portion of the total energy of the electrons ...
Hao-Xuan Gao, Jin-Jun Geng, Tian-Rui Sun, Liang Li, Yong-Feng Huang, Xue-Feng Wu   +5 more
doaj   +1 more source

Energy Spectra of Cosmic Gamma-Ray Bursts [PDF]

, 1973
T. Cline, U. D. Desai, R. W. Klebesadel, I. B. Strong   +3 more
openalex   +1 more source

Phase‐Change Materials for Volatile Threshold Resistive Switching and Neuronal Device Applications

Advanced Science, EarlyView.
Volatile threshold switching materials are an important pathway to simulate neuronal behavior. This review summarizes recent advances in the development of volatile resistive switching devices and neuronal oscillators based on three representative phase change materials, emphasizes the major challenges in this rapidly evolving field, and provides an ...
Huandong Chen, Jayakanth Ravichandran
wiley   +1 more source

A nearby long gamma-ray burst from a merger of compact objects. [PDF]

Nature, 2022
Troja E, Fryer CL, O'Connor B, Ryan G, Dichiara S, Kumar A, Ito N, Gupta R, Wollaeger RT, Norris JP, Kawai N, Butler NR, Aryan A, Misra K, Hosokawa R, Murata KL, Niwano M, Pandey SB, Kutyrev A, van Eerten HJ, Chase EA, Hu YD, Caballero-Garcia MD, Castro-Tirado AJ.   +23 more
europepmc   +1 more source

The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair

Advanced Science, EarlyView.
Synthesis of an innovative three‐layer composite antiadhesion barrier (plasmid DNA@E–H–E′) is schematically illustrated, highlighting its reactive‐oxygen‐species‐responsive, unidirectional interleukin‐37 delivery to enhance fibroblast autophagy, thereby effectively preventing tendon adhesion and promoting scarless tendon repair.
Zhenyu Sun, Jingwen Liu, Liang Chen, Zhen Wang, Fei Wang, Shen Liu   +5 more
wiley   +1 more source

Gamma-Ray Burst Pulse Structures and Emission Mechanisms

The Astrophysical Journal
The prompt phase X-ray and gamma-ray light curves of gamma-ray bursts (GRBs) exhibit erratic and complex behaviors, often with multiple pulses. The temporal shape of the individual pulses is often modeled as “fast rise exponential decay” (FRED). Here, we
A Gowri, A. Pe’er, F. Ryde, H. Dereli-Bégué   +3 more
doaj   +1 more source

HELIOS 2-Vela-Ariel 5 gamma-ray burst source position [PDF]

, 1979
T. Cline, U. D. Desai, J. H. Trainor, G. Pizzichini, A. Spizzichino, R. W. Klebesadel, M. J. Ricketts, H. F. Helmken   +7 more
openalex   +1 more source

Decoy Extracellular Vesicles Overcome Triple‐Negative Breast Cancer Heterogeneity via Membrane‐Cytoplasm‐Mitochondria Cascade Targeting

Advanced Science, EarlyView.
siT/MOF@EVs overcome TNBC heterogeneity through a tumor cell membrane–cytoplasm–mitochondria cascade effect, triggering a self‐reinforcing anti‐tumor immune cycle and durable immune memory. The system enables sequential targeting of membrane checkpoints ligands (decoy effect), cytoplasmic siRNA delivery (CSC suppression), and mitochondrial MOF ...
Chuanrong Chen, Ming Shen, Xiaofeng Wan, Lili Sheng, Na Hao, Man Li, Menglin Xu, Yang He, Jiali Zhang   +8 more
wiley   +1 more source

Polymorphism Crystal Structure Prediction with Adaptive Space Group Diversity Control

Advanced Science, EarlyView.
Polymorphic materials exhibit diverse properties despite identical compositions, but predicting their crystal structures remains challenging. This study introduces ParetoCSP2, a multi‐objective genetic algorithm incorporating genotypic age, energy, and space group diversity.
Sadman Sadeed Omee, Lai Wei, Sourin Dey, Jianjun Hu   +3 more
wiley   +1 more source