Results 121 to 130 of about 452 (208)

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Quiescent Emission from Transient Type-I X-ray Bursters

, 2004
The purpose of the funded activity was to analyze and interpret data obtained with the European Space Agency X-ray Multiple Mission (XMM) observatory, of two transiently accreting type-I X-ray bursters observed in the field, Cen X-4 and Aql X-1.
Rutledge, Robert E.
core  

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

International Journal of Cancer, EarlyView.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang, Hui Wang, Weiyan Tang, Kai Kang, Kateryna Onyshchenko, Taotao Huang, Dan Liu, Jianxin Xue, You Lu, Gabriele Niedermann, Ren Luo   +10 more
wiley   +1 more source

Exploding superstars: understanding supernovae and gamma-ray bursts

, 2009
The exceptional cosmic history and the fabulous destinies of exploding stars – supernovae and gamma-ray bursters – are highly fertile areas of research and are also very special tools to further our understanding of the universe.
Basa, Stéphane, Mazure, Alain
core  

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

In Situ Acoustic Monitoring of Focused Femtosecond Pulse Duration in Air

Laser &Photonics Reviews, EarlyView.
Air‐breakdown acoustics at the laser focus is used to determine femtosecond pulse duration with a simple USB microphone. By chirp‐tuning and compressing 1030 nm pulses from 241 to 50 fs, the acoustic amplitude scales inversely proportional to the square root of the pulse duration, enabling in situ readout over 50 fs–5 ps—crucial for precise pulse ...
Indrė Meškėlaitė, Hsin‐Hui Huang, Haoran Mu, Nguyen Hoai An Le, Tomas Katkus, Edvinas Aleksandravičius, Gabrielius Kontenis, Domas Paipulas, Saulius Juodkazis, Darius Gailevičius   +9 more
wiley   +1 more source

SNR‐Efficient Inhomogeneous Magnetization Transfer (ihMT) for Clinical Applications at 7 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Inhomogeneous MT (ihMT) is an MRI modality sensitive to Myelin, the lipid‐rich membrane surrounding the axons. A novel ihMT saturation strategy and its associated B1+$$ {\mathrm{B}}_1^{+} $$ correction at UHF are proposed. The aim is to generate a strong ihMT effect within a clinically compatible scan time while complying with SAR ...
Timothy Anderson, Niklas Wallstein, Lucas Soustelle, Thomas Troalen, Gopal Varma, David C. Alsop, Maxime Guye, Guillaume Duhamel, Olivier M. Girard   +8 more
wiley   +1 more source

Exploding Bridgewire (EBW) Detonators: An Example of Synergistic Multiphysics

Propellants, Explosives, Pyrotechnics, EarlyView.
ABSTRACT Exploding bridgewire (EBW) detonators are highly temporally reproducible explosive devices that require the rapid discharge of a high‐voltage capacitance to operate and so are immune to most of the accidental hazards associated with traditional electric detonators.
P. J. Rae, T. A. Feagin, E. M. Heatwole, R. C. Rettinger   +3 more
wiley   +1 more source

High Mass X-ray Binaries: Beacons in a Stormy Universe. [PDF]

Proc Int Astron Union, 2017
Gies DR.
europepmc   +1 more source

Linking Pulse‐Duration‐Controlled Laser Nanostructuring to Oxygen Evolution Kinetics in Fe‐enriched NiOx Electrodes

Small, EarlyView.
Pulse‐duration‐controlled ultra‐short laser processing is shown to directly create binder‐free Fe‐enriched NiOx electrodes with tunable porosity, active‐site density, and oxygen‐evolution kinetics. Shorter pulses generate defect‐rich nanostructures that accelerate charge transfer, promote highly active NiFeOOH formation, and deliver durable alkaline ...
Sandra Susan Koshy, Jyotisman Rath, Amirkianoosh Kiani   +2 more
wiley   +1 more source