Results 121 to 130 of about 3,180 (242)

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou   +3 more
wiley   +1 more source

GRB 221009A and the Apparently Most Energetic Gamma-Ray Bursts

open access: yesThe Astrophysical Journal
Gamma-ray bursts (GRBs) are often referred to as the most luminous explosions in the Universe, due to their short and highly luminous prompt emission.
Jean-Luc Atteia   +9 more
doaj   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

In Situ Acoustic Monitoring of Focused Femtosecond Pulse Duration in Air

open access: yesLaser &Photonics Reviews, EarlyView.
Air‐breakdown acoustics at the laser focus is used to determine femtosecond pulse duration with a simple USB microphone. By chirp‐tuning and compressing 1030 nm pulses from 241 to 50 fs, the acoustic amplitude scales inversely proportional to the square root of the pulse duration, enabling in situ readout over 50 fs–5 ps—crucial for precise pulse ...
Indrė Meškėlaitė   +9 more
wiley   +1 more source

Probing the Nature of High-redshift Long GRB 250114A and Its Magnetar Central Engine

open access: yesThe Astrophysical Journal
GRB 250114A is a long-duration gamma-ray burst (GRB) that triggered the Swift/Burst Alert Telescope with a spectroscopic high redshift at z = 4.732.
Wen-Yuan Yu   +4 more
doaj   +1 more source

Exploding Bridgewire (EBW) Detonators: An Example of Synergistic Multiphysics

open access: yesPropellants, Explosives, Pyrotechnics, EarlyView.
ABSTRACT Exploding bridgewire (EBW) detonators are highly temporally reproducible explosive devices that require the rapid discharge of a high‐voltage capacitance to operate and so are immune to most of the accidental hazards associated with traditional electric detonators.
P. J. Rae   +3 more
wiley   +1 more source

Advancing the Classification of Gamma-Ray Bursts Using Machine Learning. I. Gamma-Ray Bursts with Extended Emission

open access: yesThe Astrophysical Journal
Gamma-ray bursts (GRBs) with extended emission (EE) challenge traditional GRB classification schemes, yet their origins remain unknown. In this paper, we employ unsupervised machine learning methods to classify Swift EE GRBs using multidimensional ...
Xiu-Juan Li   +4 more
doaj   +1 more source

The photospheric origin of the Yonetoku relation in gamma-ray bursts. [PDF]

open access: yesNat Commun, 2019
Ito H   +5 more
europepmc   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

open access: yesPrecision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang   +13 more
wiley   +1 more source

Extremely Luminous Optical Afterglow of an Energetic Gamma-Ray Burst GRB 230204B

open access: yesThe Astrophysical Journal
Robotic telescope networks play an important role in capturing early and bright optical afterglows, providing critical insights into the energetics and emission mechanisms of GRBs.
Rahul Gupta   +49 more
doaj   +1 more source

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