Results 51 to 60 of about 3,180 (242)

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Optical and Near-infrared Observations of the Distant but Bright “New Year’s Burst” GRB 220101A

The Astrophysical Journal, 2023
High-redshift gamma-ray bursts (GRBs) are useful to probe the early Universe, but only a few candidates have been detected so far. Here, we report the optical and near-infrared observations of the afterglow of a relatively high-redshift event GRB 220101A,
Zi-Pei Zhu, Wei-Hua Lei, Daniele B. Malesani, Shao-Yu Fu, Dong-Jie Liu, Dong Xu, Paolo D’Avanzo, José Feliciano Agüí Fernández, Johan P. U. Fynbo, Xing Gao, Ana Nicuesa Guelbenzu, Shuai-Qing Jiang, David Alexander Kann, Sylvio Klose, Jin-Zhong Liu, Xing Liu, Massimiliano De Pasquale, Antonio de Ugarte Postigo, Bringfried Stecklum, Christina Thöne, Joonas Kari Markku Viuho, Yi-Nan Zhu, Jin-Da Li, He Gao, Tian-Hua Lu, Shuo Xiao, Yuan-Chuan Zou, Li-Ping Xin, Jian-Yan Wei   +28 more
doaj   +1 more source

Gamma-Ray Burst Progenitors [PDF]

Space Science Reviews, 2016
We review our current understanding of the progenitors of both long and short duration gamma-ray bursts (GRBs). Constraints can be derived from multiple directions, and we use three distinct strands; i) direct observations of GRBs and their host galaxies, ii) parameters derived from modeling, both via population synthesis and direct numerical ...
Levan, Andrew, Crowther, Paul, de Grijs, Richard, Langer, Norbert, Xu, Dong, Yoon, Sung-Chul   +5 more
openaire   +6 more sources

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

The Redshift Distribution of Einstein Probe Transients Supports Their Relation to Gamma-Ray Bursts

The Astrophysical Journal Letters
The launch of the Einstein Probe unleashed a new era of high-energy transient discovery in the largely unexplored soft X-ray band. The Einstein Probe has detected a significant number of fast X-ray transients that display no gamma-ray emission ...
Brendan O’Connor, Paz Beniamini, Eleonora Troja, Malte Busmann, Simone Dichiara, Ramandeep Gill, Jonathan Granot, Michael J. Moss, Xander J. Hall, Antonella Palmese, Niccolò Passaleva, Yu-Han Yang   +11 more
doaj   +1 more source

CLOAKED GAMMA-RAY BURSTS [PDF]

The Astrophysical Journal, 2014
It is suggested that many $γ$-ray bursts (GRBs) are cloaked by an ultra-relativistic baryonic shell that has high optical depth when the photons are manufactured. Such a shell would not fully block photons reflected or emitted from its inner surface, because the radial velocity of the photons can be less than that of the shell. This avoids the standard
openaire   +2 more sources

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

The nature of “dark” gamma-ray bursts [PDF]

Astronomy & Astrophysics, 2010
9 pages, 6 figs, A&A (accepted)
J. Greiner, T. Krühler, S. Klose, P. Afonso, C. Clemens, R. Filgas, D. H. Hartmann, A. Küpcü Yoldaş, M. Nardini, F. E. Olivares, A. Rau, A. Rossi, P. Schady, A. Updike, J. E. McEnery, J. L. Racusin, N. Gehrels   +16 more
openaire   +6 more sources

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Time-averaging Polarimetric and Spectral Properties of Gamma-Ray Bursts

The Astrophysical Journal Supplement Series
The composition and radiation mechanism of gamma-ray bursts (GRBs) within jets continue to be hotly debated. Investigating the joint polarimetric and spectral properties is crucial for understanding the composition and radiation mechanism of GRBs ...
Liang Li, Soroush Shakeri
doaj   +1 more source