Results 71 to 80 of about 3,180 (242)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

open access: yesAngewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Comprehensive Statistical Analysis of Initial Lorentz Factor and Jet Opening Angle of Gamma-Ray Bursts

open access: yesThe Astrophysical Journal
The initial Lorentz factor (Γ _0 ) and jet half-opening angle ( θ _jet ) of gamma-ray bursts (GRBs) are critical physical parameters for understanding the dynamical evolution of relativistic jets and the true energy release of GRBs.
Jian Zhang   +3 more
doaj   +1 more source

ON THE INSTANTANEOUS SPECTRUM OF GAMMA-RAY BURSTS [PDF]

open access: yesInternational Journal of Modern Physics D, 2004
A theoretical attempt to identify the physical process responsible for the afterglow emission of Gamma-Ray Bursts (GRBs) is presented, leading to the occurrence of thermal emission in the comoving frame of the shock wave which gives rise to the bursts.
R. RUFFINI   +5 more
openaire   +4 more sources

Cation Diffusion‐Mediated Displaced Reaction‐Transformation in Green Steelmaking

open access: yesAdvanced Science, EarlyView.
The removal of O lattice atoms by environmental H2 at the surface of Fe3O4 results in Fe enrichment, driving the inward diffusion of Fe cations into the bulk. Through hopping between unoccupied and initially occupied sites, cation diffusion triggers a spatially displaced reaction‐transformation and drives subsequent dynamic phase transformations and ...
Guangyi Guo   +7 more
wiley   +1 more source

Cosmology with Gamma Ray Bursts

open access: yesIl Nuovo Cimento C, 2005
8 pages, 6 figures, invited review at the 4th Workshop Gamma-Ray Bursts in the Afterglow Era, Rome,18-22 October 2004. Editors: L. Piro, L. Amati, S. Covino, and B. Gendre.
Ghisellini, G.   +4 more
openaire   +2 more sources

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

open access: yesAdvanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu   +8 more
wiley   +1 more source

RapidGBM: An Efficient Tool for Fermi-GBM Visibility Checking and Data Analysis with a Case Study of EP240617a

open access: yesThe Astrophysical Journal
We have developed a lightweight tool, RapidGBM , featuring a web-based interface and capabilities of rapid calculation of Fermi Gamma-ray Burst Monitor (GBM) visibilities and performance of basic data analysis.
Yun Wang   +17 more
doaj   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

A Gravitational Millilensing Candidate in GRB 111012A with a Possible Compact Merger Origin

open access: yesThe Astrophysical Journal
We identify GRB 111012A in the Fermi Gamma-ray Burst Monitor archive as a candidate case of gravitational millilensing. The burst shows two pulses separated by ∼3.1 s, reminiscent of previously reported lensed events such as GRB 950830 and GRB 200716C ...
Shuo Xiao   +7 more
doaj   +1 more source

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