Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess +3 more
wiley +1 more source
A New Pulsed Neutron-Gamma Density Logging Method Based on Gamma-Ray Spectra and Machine Learning. [PDF]
Dong D +8 more
europepmc +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Gamma-Ray and Thermal Neutron Shielding of Fe-Based Bilayer Composites with a Boron-Enriched Matrix and Tungsten Surface Coatings: Lead Benchmarks Included. [PDF]
Chai J +5 more
europepmc +1 more source
Unveiling the Role of Curvature in Carbon for Improved Energy Release of Ammonium Perchlorate
High‐curvature carbon materials identified via machine learning and simulation can enhance the heat release and combustion performance of ammonium perchlorate. ABSTRACT The catalytic role of carbon curvature in the thermal decomposition of ammonium perchlorate (AP) remains largely unexplored. To address this gap, this study employs machine learning and
Dan Liu +8 more
wiley +1 more source
Optimizing gamma radiation shielding of low bismuth borate glass via antimony addition: optical and physical insights. [PDF]
Hafez S, Gomaa WM, Salama E.
europepmc +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
A Comprehensive Study on Radiological Hazard Assessment and Geological Features of Gypsum Deposits. [PDF]
Hanfi MY +5 more
europepmc +1 more source

