Results 31 to 40 of about 243,821 (300)

High-Energy Cosmology: gamma rays and neutrinos from beyond the galaxy

, 2006
Our knowledge of the high-energy universe is undergoing a period of rapid change as new astronomical detectors of high-energy radiation start to operate at their design sensitivities.
A. Mücke, A.M. Bykov, A.M. Hopkins, A.W. Strong, C.D. Dermer, C.D. Dermer, Charles D. Dermer, D. Ryu, D.B. Sanders, D.F. Torres, D.F. Torres, D.J. Thompson, D.N. Spergel, E. Domingo-Santamaría, F. Aharonian, G.E. Romero, J. Albert, J. Binney, J.B.G.M. Bloemen, J.M. Paredes, K. Murase, M. Böttcher, M. Georganopoulos, O. Reimer, P. Sreekumar, P. Sreekumar, P.J.E. Peebles, S. Gabici, S.J. Sturner, T.A. Thompson, T.C. Weekes, U. Keshet, V. Bosch-Ramon, V. Pavlidou, V. Pavlidou   +34 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Is Gamma-Ray Burst 221009A Really a Once-in-10,000 yr Event?

The Astrophysical Journal
Gamma-ray bursts (GRBs) brighter than the GRB 221009A, the brightest yet observed, have previously been estimated to occur at a rate of one per 10,000 yr, based on the extrapolation of the distribution of fluences of the long-GRB population. We show that
Justin D. Finke, Soebur Razzaque
doaj   +1 more source

A future very-high-energy view of our Galaxy

, 2009
The survey of the inner Galaxy with H.E.S.S. was remarkably successful in detecting a wide range of new very-high-energy gamma-ray sources. New TeV gamma-ray emitting source classes were established, although several of the sources remain unidentified ...
Felix A. Aharonian, Frank Rieger, G. Hermann, J. A. Hinton, S. Digel, S. Funk, Werner Hofmann   +6 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Hybrid analytical method for calibrating a standard NaI(Tl) gamma-ray scintillation detector using a lateral hexagonal radioactive source [PDF]

, 2022
Mohamed S. Badawi, A. Hamzawy, Abouzeid A. Thabet   +2 more
openalex   +1 more source

A complete sample of LSP blazars fully described in $\gamma$-rays. New $\gamma$-ray detections and associations with Fermi-LAT

, 2018
We study the $\gamma$-ray and broadband spectral energy distribution (SED) properties of a complete sample of 104 bright, radio-selected low-synchrotron peaked (LSP) blazars.
Arsioli, B., Polenta, G.
core   +1 more source

On the nature of the AGILE galactic transient sources [PDF]

, 2009
The Italian gamma-ray satellite AGILE has recently reported the detection of some variable high-energy sources likely of galactic origin. These sources do not have any obvious counterpart at lower energies.
Aharonian, Blumenthal, Bogovalov, Bosch-Ramon, Bosch-Ramon, Bosch-Ramon, G. E. Romero, G. S. Vila, Grenier, Kaufman Bernadó, Kelner, Khangulyan, Levinson, Mirabel, Nolan, Punsly, Reynoso, Romero, Vila   +18 more
core   +3 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Evidence of Minijet Emission in a Large Emission Zone from a Magnetically Dominated Gamma-Ray Burst Jet

The Astrophysical Journal
The second brightest gamma-ray burst (GRB) in history, GRB 230307A, provides an ideal laboratory to study the mechanism of GRB prompt emission thanks to its extraordinarily high photon statistics and its single-episode activity.
S.-X. Yi, C.-W. Wang, X. Shao, R. Moradi, H. Gao, B. Zhang, S.-L. Xiong, S.-N. Zhang, W.-J. Tan, J.-C. Liu, W.-C. Xue, Y.-Q. Zhang, C. Zheng, Y. Wang, P. Zhang, Z.-H. An, C. Cai, P.-Y. Feng, K. Gong, D.-Y. Guo, Y. Huang, B. Li, X.-B. Li, X.-Q. Li, X.-J. Liu, Y.-Q. Liu, X. Ma, W.-X. Peng, R. Qiao, L.-M. Song, J. Wang, P. Wang, Y. Wang, X.-Y. Wen, S. Xiao, Y.-B. Xu, S. Yang, Q.-B. Yi, D.-L. Zhang, F. Zhang, H.-M. Zhang, J.-P. Zhang, Z. Zhang, X.-Y. Zhao, Y. Zhao, S.-J. Zheng   +45 more
doaj   +1 more source