Results 121 to 130 of about 5,722 (281)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Distributions of Energy, Luminosity, Duration, and Waiting Times of Gamma-Ray Burst Pulses with Known Redshift Detected by Fermi/GBM

open access: yesThe Astrophysical Journal
Discovered more than 50 years ago, gamma-ray burst (GRB) prompt emission remains the most puzzling aspect of GRB physics. Its complex and irregular nature should reveal how newborn GRB engines release their energy.
R. Maccary   +8 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

In Vivo Skin 3‐D Surface Reconstruction and Wrinkle Depth Estimation Using Handheld High Resolution Tactile Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha   +12 more
wiley   +1 more source

Real‐Time 3D Ultrasound Imaging with an Ultra‐Sparse, Low Power Architecture

open access: yesAdvanced Healthcare Materials, EarlyView.
This article presents a novel, ultra‐sparse ultrasound architecture that paves the way for wearable real‐time 3D imaging. By integrating a unique convolutional array with chirped data acquisition, the system achieves high‐resolution volumetric scans at a fraction of the power and hardware complexity.
Colin Marcus   +9 more
wiley   +1 more source

The Origin of the Coherent Radio Flash Potentially Associated with GRB 201006A

open access: yesThe Astrophysical Journal Letters
Rowlinson et al. recently claimed the detection of a coherent radio flash 76.6 minutes after a short gamma-ray burst (GRB). They proposed that the radio emission may be associated with a long-lived neutron star engine.
Nikhil Sarin   +6 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

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