Results 31 to 40 of about 70,039 (295)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Naked Forward Shock Seen in the TeV Afterglow Data of GRB 221009A

The Astrophysical Journal
We explore the implications of the light curve of the early TeV gamma-ray afterglow of GRB 221009A reported by the LHAASO Collaboration. We show that the reported offset of the reference time, T _* , allows the determination of the activation time of the
Dmitry Khangulyan, Felix Aharonian, Andrew M. Taylor   +2 more
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Search for muon-neutrino emission from GeV and TeV gamma-ray flaring blazars using five years of data of the ANTARES telescope [PDF]

, 1995
The ANTARES telescope is well-suited for detecting astrophysical transient neutrino sources as it can observe a full hemisphere of the sky at all times with a high duty cycle.
Bertin, V., Biagi, S., Bogazzi, C., Bormuth, R., Bou-Cabo, M., Bouwhuis, M. C., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Chiarusi, T., Circella, M., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Dekeyser, I., Deschamps, A., De Bonis, G., Distefano, C., Donzaud, C., Dornic, D., Drouhin, D., Dumas, A., Eberl, T., Elsaesser, D., Enzenhoefer, A., Fehn, K., Felis, I., Fermani, P., Folger, F., Fusco, L. A., Galata, S., Gay, P., Geisselsoeder, S., Geyer, K., Giordano, V., Gleixner, A., Gracia-Ruiz, R., Graf, K., Haren, H.,, Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Herrero, A., Hoessl, J., Hofestaedt, J., Hugon, C., James, C. W., Jong, M.,, Kadler, M., Kalekin, O., Katz, U., Kiessling, D., Kooijman, P., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Lambard, G., Lattuada, D., Lefèvre, Dominique, Leonora, E., Loucatos, S., Mangano, S., Marcelin, M., Margiotta, A., Martinez-Mora, J. A., Martini, S., Mathieu, A., Michael, T., Migliozzi, P., Moussa, A., Mueller, C., Neff, M., Nezri, E., Pavalas, G. E., Pellegrino, C., Perrina, C., Piattelli, P., Popa, V., Pradier, T., Racca, C., Riccobene, G., Richter, R., Roensch, K., Rostovtsev, A., Saldana, M., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schmid, J., Schnabel, J., Schulte, S., Schuessler, F., Seitz, T., Sieger, C., Spurio, M., Steijger, J. J. M., Stolarczyk, Th., Sanchez-Losa, A., Taiuti, M., TAMBURINI, Christian, Trovato, A., Tselengidou, M., Toennis, C., Turpin, D., Vallage, B., Vallée, Corentin, Van Elewyck, V., Visser, E., Vivolo, D., Wagner, S., Wilms, J., Zornoza, J. D., Zúñiga, J., Collaboration, ANTARES, Adrián-Martínez, S., Albert, A., André, M., Anton, G., Ardid, M., Aubert, J. J., Baret, B., Barrios-Marti, J., Basa, S.   +127 more
core   +2 more sources

Instrument for observing transient cosmic gamma-ray sources for the ISEE-C Heliocentric spacecraft [PDF]

, 1977
Satellite instrumentation that would serve as one element of a three-satellite network to provide precise directional information for the recently discovered cosmic gamma-ray bursts is described. The proposed network would be capable of determining source locations with uncertainties of less than one arc minute, sufficient for a meaningful optical and ...
Evans, W.D., Aiello, W.P., Klebesadel, R.W.   +2 more
openaire   +2 more sources

Effects of dead time losses on terrestrial gamma ray flash measurements with the Burst and Transient Source Experiment [PDF]

Journal of Geophysical Research: Space Physics, 2010
Measurements from the Burst and Transient Source Experiment (BATSE) instrument on the Compton Gamma Ray Observatory (CGRO) are the only ones where characteristics of single terrestrial gamma ray flashes (TGFs) have been obtained thus far. However, it has been reported that the measurements suffer from significant dead time losses which complicates the ...
Gjesteland, Thomas, Østgaard, Nikolai, Connell, P. H., Stadsnes, J., Fishman, G. J.   +4 more
openaire   +3 more sources

Al–Cu Composite Casting of Laser‐Deoxidized Copper: Bonding, Interfacial Chemistry, and Thermal Conductivity

Advanced Engineering Materials, EarlyView.
This study investigates laser‐based oxide removal of Cu inserts in oxygen‐free conditions and examines long‐term oxidation kinetics and surface chemistry under different atmospheres via X‐ray photoelectron spectroscopy. Al–Cu compound casting with differently oxidized surfaces is performed, and intermetallic phase formation, morphology, and thermal ...
Timon Steinhoff, Finn‐Lennard Janthur, Sascha Zimmermann, Sarah Seffer, Jörg Hermsdorf, René Gustus, Ludger Overmeyer, Wolfgang Maus‐Friedrichs, Hans Jürgen Maier, Christian Klose   +9 more
wiley   +1 more source

Transient X-ray sources in the field of the unidentified gamma-ray source TeV J2032+4130 in Cygnus

Astrophysics and Space Science, 2007
We present an analysis of Chandra ACIS observations of the field of TeV J2032+4130, the first unidentified TeV source, detected serendipitously by HEGRA. This deep (48.7 ksec) observation of the field follows up on an earlier 5 ksec Chandra director's discretionary observation.
Mukherjee, R., Gotthelf, E. V., Halpern, J. P.   +2 more
openaire   +2 more sources

Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy

Advanced Engineering Materials, EarlyView.
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb, Zachary T. Kloenne, Samuel R. Rogers, Chi Hang Dominik Kwok, Mark C. Hardy, Michele S. Conroy, David Dye   +6 more
wiley   +1 more source

Evidence of Minijet Emission in a Large Emission Zone from a Magnetically Dominated Gamma-Ray Burst Jet

The Astrophysical Journal
The second brightest gamma-ray burst (GRB) in history, GRB 230307A, provides an ideal laboratory to study the mechanism of GRB prompt emission thanks to its extraordinarily high photon statistics and its single-episode activity.
S.-X. Yi, C.-W. Wang, X. Shao, R. Moradi, H. Gao, B. Zhang, S.-L. Xiong, S.-N. Zhang, W.-J. Tan, J.-C. Liu, W.-C. Xue, Y.-Q. Zhang, C. Zheng, Y. Wang, P. Zhang, Z.-H. An, C. Cai, P.-Y. Feng, K. Gong, D.-Y. Guo, Y. Huang, B. Li, X.-B. Li, X.-Q. Li, X.-J. Liu, Y.-Q. Liu, X. Ma, W.-X. Peng, R. Qiao, L.-M. Song, J. Wang, P. Wang, Y. Wang, X.-Y. Wen, S. Xiao, Y.-B. Xu, S. Yang, Q.-B. Yi, D.-L. Zhang, F. Zhang, H.-M. Zhang, J.-P. Zhang, Z. Zhang, X.-Y. Zhao, Y. Zhao, S.-J. Zheng   +45 more
doaj   +1 more source