Results 91 to 100 of about 1,403,017 (284)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Individualized Prediction of Meningioma Response to Gamma Knife Radiosurgery Using Nested Consensus Machine Learning with 3D Fractal, Lacunarity and Radiomic Features from MRI

Fractal and Fractional
Background: This study aimed to develop a fully nested, information leakage-free machine-learning workflow to predict the volumetric response of meningioma to Gamma Knife radiosurgery (GKRS) from pre-treatment MRI and to compare the predictive value of ...
Herwin Speckter, Marko Radulovic, Ivan Gonzalez, Giancarlo Hernandez, Jose Bido, Diones Rivera, Luis Suazo, Santiago Valenzuela, Ismael Peralta, Jeffrey Paulino, Teuddis Bernard, Issael Ramirez, Peter Stoeter, Velicko Vranes   +13 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Measurement of the gamma gamma* --> eta and gamma gamma* --> eta' transition form factors

, 2011
Comment: 21 pages, 18 postscript figures, published ...
Sanchez P. del Amo, Lees J. P., Poireau V., Prencipe E., Tisserand V., Garra Tico J., Grauges E., Martinelli M., Milanes D. A., Palano A., Pappagallo M., Eigen G., Stugu B., Sun L., Brown D. N., Kerth L. T., Kolomensky Y.u. G., Lynch G., Osipenkov I. L., Koch H., Schroeder T., Asgeirsson D. J., Hearty C., Mattison T. S., McKenna J. A., Khan A., Blinov V. E., Botov A. A., Buzykaev A. R., Druzhinin V. P., Golubev V. B., Kravchenko E. A., Onuchin A. P., Serednyakov S. I., Skovpen Y.u. I., Solodov E. P., Todyshev K. Y.u., Yushkov A. N., Bondioli M., Curry S., Kirkby D., Lankford A. J., Mandelkern M., Martin E. C., Stoker D. P., Atmacan H., Gary J. W., Liu F., Long O., Vitug G. M., Campagnari C., Hong T. M., Kovalskyi D., Richman J. D., West C. A., Eisner A. M., Heusch C. A., Kroseberg J., Lockman W. S., Martinez A. J., Schalk T., Schumm B. A., Seiden A., Winstrom L. O., Cheng C. H., Doll D. A., Echenard B., Hitlin D. G., Ongmongkolkul P., Porter F. C., Rakitin A. Y., Andreassen R., Dubrovin M. S., Meadows B. T., Sokoloff M. D., Bloom P. C., Ford W. T., Gaz A., Nagel M., Nauenberg U., Smith J. G., Wagner S. R., Ayad R., Toki W. H., Jasper H., Petzold A., Spaan B., Kobel M. J., Schubert K. R., Schwierz R., Bernard D., Verderi M., Clark P. J., Playfer S., Watson J. E., Andreotti M., Bettoni D., Bozzi C., Calabrese R., Cecchi A., Cibinetto G., Fioravanti E., Franchini P., Garzia I., Luppi E., Munerato M., Negrini M., Petrella A., Piemontese L., Baldini Ferroli R., Calcaterra A., de Sangro R., Finocchiaro G., Nicolaci M., Pacetti S., Patteri P., Peruzzi I. M., Piccolo M., Rama M., Zallo A., Contri R., Guido E., Lo Vetere M., Monge M. R., Passaggio S., Patrignani C., Robutti E., Bhuyan B., Prasad V., Lee C. L., Morii M., Edwards A. J., Adametz A., Marks J., Uwer U., Bernlochner F. U., Ebert M., Lacker H. M., Lueck T., Volk A., Dauncey P. D., Tibbetts M., Behera P. K., Mallik U., Chen C., Cochran J., Crawley H. B., Meyer W. T., Prell S., Rosenberg E. I., Rubin A. E., Gritsan A. V., Guo Z. J., Arnaud N., Davier M., Derkach D., da Costa J. Firmino, Grosdidier G., Le Diberder F., Lutz A. M., Malaescu B., Perez A., Roudeau P., Schune M. H., Serrano J., Sordini V., Stocchi A., Wang L., Wormser G., Lange D. J., Wright D. M., Bingham I., Chavez C. A., Coleman J. P., Fry J. R., Gabathuler E., Hutchcroft D. E., Payne D. J., Touramanis C., Bevan A. J., Di Lodovico F., Sacco R., Sigamani M., Cowan G., Paramesvaran S., Wren A. C., Brown D. N., Davis C. L., Denig A. G., Fritsch M., Gradl W., Hafner A., Alwyn K. E., Bailey D., Barlow R. J., Jackson G., Lafferty G. D., Anderson J., Cenci R., Jawahery A., Dallapiccola C., Sciacca C., Raven G., Corwin L. A., Strom D., Strube J., Bomben M., CALDERINI, GIOVANNI, Marchiori G., Ocariz J., ANGELINI, CARLO, BATIGNANI, GIOVANNI, BETTARINI, STEFANO, Casarosa G., FORTI, FRANCESCO, GIORGI, MARCELLO, PAOLONI, EUGENIO, RIZZO, GIULIANA, Adye T., de Monchenault G. Hamel, Vasseur G., Benitez J. F., Lewis P., Su D., Bellis M., Lanceri L., Albert J., Banerjee S.w., Kowalewski R., Roney J. M., Latham T. E., Dasu S., Wu S. L.   +232 more
openaire   +8 more sources

Stereotactic Gamma Knife Radiosurgery for Merkel cell carcinoma brain metastases: case report and systematic review of literature

Brain and Spine
Introduction: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin malignancy with an increasing incidence. Although it frequently presents with loco-regional metastases, brain metastases (BMs) are exceptionally rare, lacking ...
Octavian Vatavu, Francesco Maria Crisà, Filippo Leocata, Virginia Arienti, Marco Cenzato, Alessandro La Camera   +5 more
doaj   +1 more source

Retomando o futuro: a reconstrução de si por meio de grupos de apoio = Retaking the future: rebuilding the self through support groups = Reanudar el futuro: reconstruirse a través de grupos de apoyo

Civitas - Revista de Ciências Sociais, 2022
Neste artigo, por meio de uma pesquisa qualitativa envolvendo observações e entrevistas, analiso dois “grupos de apoio” na cidade do Rio de Janeiro que assistem a pessoas que tiveram um grave contato com a morte, direta ou indiretamente.
Talone, Vittorio da Gamma
doaj  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Redaksi dan Pedoman Penulisan Jurnal Gamma, Vol 7, No. 2, Maret 2014

, 2014
Redaksi dan Pedoman Penulisan Jurnal Gamma, Vol 7, No.
Pedoman Penulisan, Redaksi &
core   +1 more source

Dampak Perdagangan Lintas Batas Terhadap Perekonomian Masyarakat Lokal (Studi Kasus: Wilayah Perbatasan RI-PNG di Distrik Muara Tami)

Jurnal Ekonomi dan Studi Pembangunan, 2015
Some things are concerns in this study is to see what factors are the main attraction for people of PNG to spend their money in Indonesia (Skow-Wutung market), so the business man in downtown Jayapura initiative to trade with the people of PNG directly ...
Sinyo Gamma Timisela
doaj