Results 41 to 50 of about 187,405 (281)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The stability of Cauchy's gamma–beta functional equation

open access: yesJournal of Mathematical Analysis and Applications, 2004
The authors prove the superstability of the functional equation \[ B(x,y)f(x,y)=f(x)f(y), \] where \(B(x,y)\) is the beta function of Euler and also prove the stability of this equation in the sense of R. Ger.
Lee, Young Whan, Choi, Byung Mun
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Inequalities for Beta and Gamma functions via some classical and new integral inequalities

open access: yesJournal of Inequalities and Applications, 2000
In this survey paper we present the natural applications of certain integral inequalities such as Chebychev's inequality for synchronous and asynchronous mappings, Hölder's inequality and Grüss' and Ostrowski's inequalities for the celebrated ...
Agarwal RP, Dragomir SS, Barnett NS
doaj  

q-Gamma and q-Beta Functions [PDF]

open access: yes, 2002
Being related to solutions of special types of differential equations, many important functions in analysis are defined in terms of definite integrals.
Victor Kac, Pokman Cheung
openaire   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A New type of Connected Sets via Bioperations

open access: yesInternational Journal of Analysis and Applications, 2018
The purpose of this paper is to introduce the notion of $\alpha_{(\gamma, \gamma^{'})}$-separated sets and study their properties in topological spaces, then we introduce the notions of $\alpha_{(\gamma, \gamma^{'})}$-connected and $\alpha_{(\gamma ...
Hariwan Z. Ibrahim
doaj   +2 more sources

Extension of Two Parameter Gamma, Beta Functions and Its Properties [PDF]

open access: yes, 2020
In this paper, we introduce the extension of the p-k Gamma function and the p-k Beta function. This extension of the p-k Gamma function is named as p-k-b Gamma function and an extension of the beta function is p-k-b Beta function.
Gehlot, Kuldeep S.   +1 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Comparison of X-ray and gamma-ray dose-response curves for pink somatic mutations in Tradescantia clone 02 [PDF]

open access: yes, 1976
Microdosimetric data indicate that the mean specific energy,zeta, produced by individual charged particles from X rays and gamma rays is different for the two radiation qualities by nearly a factor of two.
Mills, R. E.   +3 more
core   +1 more source

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