Results 111 to 120 of about 1,406,358 (336)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Symmetric and Asymmetric Double Series via Expansions over Legendre Polynomials

open access: yesAxioms
By examining Fourier–Legendre series pairs F(y) and G(y), fifteen classes of symmetric and asymmetric bivariate series will systematically be investigated. A compendium of 360 remarkable summation formulae will be established.
Mei Bai, Wenchang Chu
doaj   +1 more source

Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model [PDF]

open access: gold, 2022
Connie A. Mackenzie-Gray Scott   +8 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

$\gamma-$OPEN FUNCTION AND $\gamma-$CLOSED FUNCTIONS [PDF]

open access: yesInternational Journal of Apllied Mathematics, 2019
S. Haxha, Q.D. Gjonbalaj
openaire   +1 more source

Some Representations of the Modified Degenerate Gamma Matrix Function [PDF]

open access: yesSahand Communications in Mathematical Analysis
The main goal of this article is to extend the concept of special matrix functions through the study of modified degenerate Gamma matrix function. For this, the modified degenerate Gamma matrix function has been introduced and some of its properties have
İnci Ege, Kwara Nantomah
doaj   +1 more source

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