A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Incomplete Gamma functions for evaluating Erlang process probabilities [PDF]
, 1963 John R. B. Whittlesey
openalex +2 more sources
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Global calibrations for the non-homogeneous Mumford-Shah functional
, 2001 Using a calibration method we prove that, if $\Gamma\subset \Omega$ is a closed regular hypersurface and if the function $g$ is discontinuous along $\Gamma$ and regular outside, then the function $u_{\beta}$ which solves $$ \begin{cases} \Delta u_{\beta}=
Morini, Massimiliano
core +1 more source
A methodical contribution to the theory of Gamma function. [I.] [PDF]
, 1903 Vilém Jung
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
On the role of three functions in the Riemann literatures
, 2019 In Riemann's paper and Nachlass on the zeta function, $\pi^{-\frac{s}{2}}\Gamma(\frac{s}{2})\zeta(s)$ has three different functional expressions, of which $$\pi^{-\frac{s}{2}}\Gamma(\frac{s}{2})\zeta(s)=2\Re[\pi^{-\frac{s}{2}}\Gamma(\frac{s}{2})f(s ...
Feng, Nianrong, Wang, Yongzheng
core
On the zeros of the function $\beta(z)$ associated with the gamma function [PDF]
, 1926 T. H. Gronwall
openalex +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Some properties of k-gamma and k-beta functions
ITM Web of Conferences, 2016 In this paper, firstly, we introduce the several definitions of classic gamma function and beta function, and the several definitions of k-gamma function and k-beta function.
Wang Wu-Sheng
doaj +1 more source