Results 121 to 130 of about 869,976 (254)

Exploring the Clinical Diversity of Castleman Disease and TAFRO Syndrome: A Japanese Multicenter Study on Lymph Node Distribution Patterns

open access: yesAmerican Journal of Hematology, Volume 100, Issue 4, Page 592-605, April 2025.
ABSTRACT Individuals diagnosed with Castleman disease (CD) and TAFRO syndrome (characterized by thrombocytopenia, anasarca, fever, bone marrow fibrosis, and organomegaly) displays a wide range of clinical symptoms, including varying patterns of lymph node enlargement, systemic inflammation, and impaired organ function.
Mizuna Otsuka   +18 more
wiley   +1 more source

A Case Report of IgA‐κ Type Multiple Myeloma Complicated With Hyperlipidemia

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT In the majority of cases, patients with multiple myeloma (MM) generally exhibit normal or decreased blood lipid levels. However, a minority of cases demonstrate the significant role of M protein in elevated lipid levels, particularly in the close association between IgA type MM and hypertriglyceridemia and hypercholesterolemia. Here, we report
Jie Li   +5 more
wiley   +1 more source

Chronic Viral Infections and Al Amyloidosis: An Uncommon Association

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT AL‐amyloidosis is caused by deposition of pathological insoluble proteins in organs and tissues. HIV infection is a multi‐system disorder causing chronic inflammation. We report a case of AL‐amyloidosis associated with HIV suggesting that HIV‐associated immune dysregulation might be critical for pathogenesis of plasma cells dyscrasias and then
Alberto Palladini   +7 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Exploring Cryoglobulinemia's Clinical Odyssey: A Case Series

open access: yeseJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Cryoglobulinemia (CG) encompasses disorders in which immunoglobulins precipitate at low temperatures. According to Brouet's classification, Type I CG is linked to plasma cell disorders, while mixed CG (Types II and III) is associated with autoimmune conditions, infections (notably hepatitis C virus [HCV]), and lymphoproliferative disorders ...
Shivangini Duggal   +5 more
wiley   +1 more source

Identification of diagnostic and therapeutic biomarkers for attention‐deficit/hyperactivity disorder

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 41, Issue 4, April 2025.
Abstract Attention‐deficit/hyperactivity disorder (ADHD) is a common psychiatric condition among children and adolescents, often associated with a high risk of psychiatric comorbidities. Currently, ADHD diagnosis relies exclusively on clinical presentation and patient history, underscoring the need for clinically relevant, reliable, and objective ...
Sheng‐Yu Lee   +2 more
wiley   +1 more source

Targeting Frequent Efferocytosis in Tumor Microenvironment is a New Direction for Cancer Treatment

open access: yesSmall Science, Volume 5, Issue 4, April 2025.
Phagocytosis of “apoptotic tumor cells”, known as efferocytosis, accelerates the formation of an immunosuppressive microenvironment, leading to the detriment of tumor therapy. Blocking this process represents one of the novel approaches for treating tumors.
Gangxing Zhu   +9 more
wiley   +1 more source

Pharmacogenomics of coronary artery response to intravenous gamma globulin in kawasaki disease. [PDF]

open access: yesNPJ Genom Med
Shrestha S   +13 more
europepmc   +1 more source

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