Results 31 to 40 of about 39,193 (264)

Hematopoietic stem cells transplant in patients with common variable immunodeficiency. Is a therapeutic option?

open access: yesRevista Alergia México, 2017
Background: Patients with common variable immunodeficiency show higher incidence of sinopulmonary and gastrointestinal infections, as well as lymphoproliferative and autoimmune diseases.
Julio César Cambray-Gutiérrez   +4 more
doaj   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

open access: yesAdvanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu   +8 more
wiley   +1 more source

Study of Serum Protein Profiles in Burn Patients

open access: yesIndian Journal of Plastic Surgery, 1993
66 patients of varying degrees of burns were divided in 6 groups on % of total body surface burns. Serum electrophoresis studies on all, were carried out at definite Intervals. Total (i) Serum proteins, (ii) Albumin globulin ratio and (iii) Alfal, Alfa2,
Dr. R.K. Mahajan   +3 more
doaj   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD

open access: yesJurnal Kedokteran Hewan, 2021
The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which  included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma ...
Lia Khairita   +3 more
doaj   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

open access: yesAdvanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang   +12 more
wiley   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki   +9 more
wiley   +1 more source

Primary intestinal lymphangiectasia: twenty years of experience at a Mexican tertiary care hospital

open access: yesRevista de Gastroenterología de México (English Edition), 2014
Background: Primary intestinal lymphangiectasia is a rare congenital disease described by Waldmann in 1961 that is a consequence of obstruction of the lymphatic drainage of the small bowel with secondary lymph vessel dilation.
D. Valdovinos-Oregón   +7 more
doaj   +1 more source

THE USE OF PLASMATIC AND SALIVARY PROTEIN FRACTIONS FOR ASSESSING CARIOACTIVITY IN PATIENTS WITH CHRONIC LIVER DISEASE OF ALCOHOLIC ETIOLOGY [PDF]

open access: yesRomanian Journal of Medical Practice, 2018
Objectives. To determine the correlations between carioactivity, quantified by the cariogenic index, and total plasma proteins, protein fractions and salivary immunoglobulins. Material and method.
Daniela G. Balan   +9 more
doaj   +1 more source

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