Results 81 to 90 of about 9,126 (172)

Nutritional composition of pollen stores in managed bees across European agro‐ecosystems reveals species‐specific differences but limited pesticide effects

Ecological Entomology, EarlyView.
In the pollen stores of three bee species deployed across 128 European sites, bumble bees harboured lower lipid content and higher protein‐to‐lipid ratios than honey bees and mason bees. Toxicity‐weighted pesticide risk did not alter protein‐to‐lipid ratios, but higher risk was associated with reduced protein and lipid content in the pollen stores of ...
Antoine Gekière, Clément Tourbez, Maryse Vanderplanck, Tomasz Kiljanek, Guillaume Ghisbain, Elif Kardas, Irene Bottero, Marie‐Pierre Chauzat, Elena Cini, Francesca Corvucci, Joachim R. de Miranda, Gennaro Di Prisco, Christophe Dominik, Francesca V. Grillenzoni, Simon Hodge, Anina Knauer, Marion Laurent, Vicente Martínez‐López, Risto Raimets, Janine M. Schwarz, Deepa Senapathi, Giorgia Serra, Giovanni Tamburini, Dimitry Wintermantel, Mark J. F. Brown, Matthias Albrecht, Cecilia Costa, Pilar De la Rúa, Alexandra‐Maria Klein, Marika Mänd, Simon G. Potts, Maj Rundlöf, Oliver Schweiger, Jane C. Stout, Denis Michez   +34 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome [PDF]

Open Veterinary Journal, 2015
A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma.
I. Lippi, F. Perondi, S.J. Ross, V. Marchetti, G. Lubas, G. Guidi   +5 more
doaj  

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

A Fusion Between Common Bean Phaseolin and the N‐Terminal Domain of Maize 16 kDa Gamma Zein: Clues for Designing Nutritionally Improved Seed Storage Proteins

Plant Biotechnology Journal, EarlyView.
ABSTRACT Increasing the nutritional value of seed storage proteins (SSPs) has been largely hindered by limited knowledge of how the features of the various SSP domains determine high accumulation in protein storage vacuoles (PSV) or as endoplasmic reticulum (ER)‐located insoluble protein bodies (PB).
Emma Costa, Lucrezia Luciani, Mahsa Taghipour Rahimi, Alessandro Vitale, Emanuela Pedrazzini   +4 more
wiley   +1 more source

Gamma gap and albumin-globulin ratio show poor sensitivity for monoclonal gammopathy screening in South Africa

African Journal of Laboratory Medicine
Background: Monoclonal gammopathies, including multiple myeloma, present significant challenges in sub-Saharan Africa. Diagnosis is often missed because of limited screening tools.
Njabulo Khumalo, Cameron A. Francis, Siphiwe M. Baloyi, Jody A. Rusch   +3 more
doaj   +1 more source

The role of acquired host immunity in periodontal diseases

Periodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane, David F. Lappin, Shauna Culshaw   +2 more
wiley   +1 more source

Clinical implications of imlifidase interference in antibody screening and transfusion management

Transfusion, EarlyView.
Abstract Background Imlifidase has received conditional approval from the EMA for desensitizing deceased donor kidney transplant recipients. It works by cleaving IgG into F(ab′)2 and Fc fragments, thereby reducing the risk of antibody‐mediated rejection. However, its impact on diagnostic assays remains understudied. Case Report We present the case of a
Zgjim Osmani, Aiko P. J. de Vries, Arjan Albersen   +2 more
wiley   +1 more source

IrregulAB: An open‐source rule‐based engine for automated red cell antibody panel interpretation

Transfusion, EarlyView.
Abstract Background Interpretation of antibody identification panels remains a manual, expertise‐intensive step in transfusion testing; interpretive errors and long turnaround times persist even in well‐equipped hospitals. Existing commercial software is closed source and often omits enzyme‐phase, cold‐phase, and dosage‐sensitive exclusion rules ...
Davide Crucitti, Violeta Vidal Ballester, Jesús Gómez Fernández, Eugenia Fernandez Mellid, Angie Lizeth Ruge Perdomo, Carlos Pérez Míguez, Adrián Mosquera Orgueira   +6 more
wiley   +1 more source

Codocytosis in the Dog: 345 Cases (2020–2022)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker, Maria Jaramillo, Brad D. Cingolani, Floyd L. Williams Jr., Priscila B. S. Serpa, Andrew D. Woolcock   +5 more
wiley   +1 more source