Results 31 to 40 of about 234,241 (214)
Interdisciplinary Perspectives on Infectious Diseases, 2016 Although interferon-gamma, interleukin-10, and adiponectin are key immunopathogenesis mediators of tuberculosis, their association with clinical manifestations of early stage disease is inconclusive.
Nathan Shaviya +3 more
doaj +1 more source
Growth index of matter perturbations in the light of Dark Energy Survey
European Physical Journal C: Particles and Fields, 2020 We study how the cosmological constraints from growth data are improved by including the measurements of bias from Dark Energy Survey (DES). In particular, we utilize the biasing properties of the DES Luminous Red Galaxies (LRGs) and the growth data ...
Spyros Basilakos +1 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Natural radioactivity assessment in the sands from Tirunelveli District, Tamil Nadu, India
Radiation Protection and EnvironmentNatural sand, which is predominantly observed in river bottoms, is widely used in construction projects. In the current study, the NaI (Tl) gamma-ray spectrometer was employed to evaluate the natural radioactivity caused by the presence of 226Ra, 232Th ...
F. S. Karolin Mary, G. Shanthi
doaj +1 more source
Scientific African, 2020 Background: Awareness of the dangers associated with exposure to high radiation in the environment is necessary to avoid its health impact, especially when staying in-door.
Emmanuel Sunday Joel +7 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Observational constraints on growth index with cosmography
European Physical Journal C: Particles and Fields, 2019 In the literature, it was proposed that the growth index $$\gamma $$ γ is useful to distinguish the scenarios of dark energy and modified gravity. In the present work, we consider the constraints on the growth index $$\gamma $$ γ by using the latest ...
Zhao-Yu Yin, Hao Wei
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A Study on the Influence of Speed on Road Roughness Sensing: The SmartRoadSense Case
Sensors, 2017 SmartRoadSense is a crowdsensing project aimed at monitoring the conditions of the road surface. Using the sensors of a smartphone, SmartRoadSense monitors the vertical accelerations inside a vehicle traveling the road and extracts a roughness index ...
Giacomo Alessandroni +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source