Results 51 to 60 of about 170,362 (288)

Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study

open access: yesRadiation Oncology, 2023
Background Beam matching is a concept in radiotherapy applied to clinics where more than one linac is employed to harmonise beam characteristics across linacs for allowing patients interchange without replanning.
Diana M. Ghemiș   +3 more
doaj   +1 more source

Particle acceleration in the vacuum gaps in black hole magnetospheres

open access: yes, 2016
We consider particle acceleration in vacuum gaps in magnetospheres of black holes powered through Blandford-Znajek mechanism and embedded into radiatively-inefficient accretion flow (RIAF) environment.
Neronov, A., Ptitsyna, K.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Circumstellar disks in binary star systems

open access: yes, 2012
In this paper we study the evolution of viscous and radiative circumstellar disks under the influence of a companion star. We focus on the eccentric {\gamma} Cephei and {\alpha} Centauri system as examples and compare the disk quantities such as disk ...
Artymowicz   +49 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

HyperArcTM Dosimetric Validation for Multiple Targets Using Ionization Chamber and RT-100 Polymer Gel

open access: yesGels, 2022
Multiple brain metastases single-isocenter stereotactic radiosurgery (SRS) treatment is increasingly employed in radiotherapy department. Before its use in clinical routine, it is recommended to perform end-to-end tests.
Lucia Zirone   +10 more
doaj   +1 more source

Tidal Destruction of The First Dark Microhalos [PDF]

open access: yes, 2006
We point out that the usual self-similarity in cold dark matter models is broken by encounters with individual normal galactic stars on sub-pc scale. Tidal heating and stripping must have redefined the density and velocity structures of the population of
Angus, Garry W.   +4 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Passing to the Limit in a Wasserstein Gradient Flow: From Diffusion to Reaction [PDF]

open access: yes, 2011
We study a singular-limit problem arising in the modelling of chemical reactions. At finite {\epsilon} > 0, the system is described by a Fokker-Planck convection-diffusion equation with a double-well convection potential.
A. Blanchet   +35 more
core   +6 more sources

Gamma passing rates of daily EPID transit images correlate to PTV coverage for breast cancer IMRT treatment plans

open access: yesJournal of Applied Clinical Medical Physics, 2023
AbstractPurposeThe use of the transit image obtained with the electronic portal‐imaging device (EPID) is becoming an extended method to perform in‐vivo dosimetry. The transit images acquired during each fraction can be compared with a predicted image, if available, or with a baseline image, usually the obtained in the first fraction.
Duch Guillen, María Amor   +5 more
openaire   +5 more sources

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