Results 71 to 80 of about 25,193 (285)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems

Frontiers in Oncology
ObjectiveThis study investigates the impact of non-standard positioning on the accuracy of 6D-skull tracking using dual-panel imaging systems. It explores whether positioning patients’ heads at various angles during intracranial lesion treatment affects ...
He Huang, Lian Zhang, Yunfei Bian, Yang Dong, Hongyu Lin, Hui Xu, Ying Li   +6 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Study of impacts of different evaluation criteria on gamma pass rates in VMAT QA using MatriXX and EPID [PDF]

Polish Journal of Medical Physics and Engineering, 2017
Abstract Aim: This study evaluates the impacts of using different evaluation criteria on gamma pass rates in two commercially available QA methods employed for the verification of VMAT plans using different hypothetical planning target volumes (PTVs) and anatomical regions.
Manthala Padannayil Noufal, Kallikuzhiyil Kochunny Abdullah, Puzhakkal Niyas, Pallimanhayil Abdul Raheem Subha   +3 more
openaire   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Predictive gamma passing rate for three-dimensional dose verification with finite detector elements via improved dose uncertainty potential accumulation model [PDF]

内容の要約博士(医学)Doctor of Philosophy in Medical ...
Shiba, Eiji
core   +1 more source

Whole brain radiation therapy verification using 2D gamma analysis method [PDF]

, 2020
Whole-brain radiation therapy (WBRT) is a standard radiotherapy treatment for the patients with multiple brain metastases. The efficiency of the dose calculation algorithm and the accuracy of the dose delivered to the patient is crucial in radiotherapy ...
Zainodin, Nik Nurul Afina Wan
core  

Validation of a Newly Installed Secondary Independent Dose Verification System [PDF]

, 2022
: The aim of the study was to validate a newly installed Mobius 3D (M3D) quality assurance software for use as a secondary independent dose verification system for comparison with an Eclipse treatment planning system (TPS) data of 3D conformal ...
Tagoe, Samuel Nii Adu; Korle Bu Teaching Hospital, School of Biomedical & Allied Health Sciences, University of Ghana, KB 369, Korle Bu, Accra, Ghana, Ndonye, Philip Kioko; The Nairobi Hospital, Cancer Treatment Center, P.O Box 30026, Code 00100, NAIROBI, KENYA   +1 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Three-dimensional dose comparison of flattening filter (FF) and flattening filter-free (FFF) radiation therapy by using NIPAM gel dosimetry.

PLoS ONE, 2019
Intensity-modulated radiotherapy and volumetric modulated arc therapy are modern radiation therapy technologies that can create the desired dose distribution by multileaf collimator movement and dose-rate control.
Chun-Hsu Yao, Tung-Hao Chang, Chia-Chi Lin, Yuan-Chun Lai, Chin-Hsing Chen, Yuan-Jen Chang   +5 more
doaj   +1 more source