Results 241 to 250 of about 164,677 (312)

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

Zeolitic Imidazolate Framework-8 (ZIF-8) as a Carrier for Kaempferol Delivery to Protect Against Gamma Radiation-Induced Mortality and Damage. [PDF]

Pharmaceutics
Yang G, Wang J, Wang R, Han L, Gong C, Chen J, Chen M, Yuan Y.   +7 more
europepmc   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Comparative analysis of Monte Carlo simulations and experimental evaluation of PMMA reinforced with hgo for gamma radiation shielding. [PDF]

Sci Rep
Mokhtari Dorostkar M, Abdi Saray A.
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Gamma radiation-induced molecular toxicity and effects on pluripotent stem cells of the radiosensitive conifer Norway spruce (Picea abies). [PDF]

Planta
Bhattacharjee P, Lee Y, Viejo M, Gillard GB, Sandve SR, Hvidsten TR, Salbu B, Brede DA, Olsen JE.   +8 more
europepmc   +1 more source

Development of PMMA composites with tungsten trioxide for improved gamma radiation shielding in microsatellites. [PDF]

Sci Rep
Hesham N, Abu-Zeid HM, Nada A, Yahia IS, Hussien MSA, Diab HM, Ali MA, Mosleh AT, Elfiky D.   +8 more
europepmc   +1 more source

Gamma Radiation Shielding Efficiency of Cross-Linked Polystyrene-b-Polyethyleneglycol Block Copolymer Nanocomposites Doped Arsenic (III) Oxide and Boron Nitride Nanoparticles. [PDF]

Polymers (Basel)
Ortaç B, Baskan T, Mutlu S, Yilmaz SS, Yilmaz AH.   +4 more
europepmc   +1 more source

Production and optimization of polyglutamic acid from Bacillus licheniformis: effect of low levels of gamma radiation. [PDF]

AMB Express
Youssef RM, Samir R, Gomaa OM, ElHifnawi HN, Ramadan MA.   +4 more
europepmc   +1 more source

Comparing the Accuracy of Soil Moisture Estimates Derived from Bulk and Energy-Resolved Gamma Radiation Measurements. [PDF]

Sensors (Basel)
Akter S, Huisman JA, Bogena HR.
europepmc   +1 more source