Results 91 to 100 of about 89,948 (288)

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

open access: yes, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker   +8 more
core   +2 more sources

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

open access: yesAdvanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu   +20 more
wiley   +1 more source

Periodicity in wide-band time series [PDF]

open access: yes, 2002
Summary: To test the hypotheses that (i) electroencephalograms (EEGs) are largely made up of oscillations at many frequencies and (ii) that the peaks in the power spectra represent oscillations, we applied a new method, called the Period Specific ...
Bullock, T.H.   +2 more
core  

Analysis of DNA-Damage Response to ionizing radiation in serum-shock synchronized human fibroblasts. [PDF]

open access: yes, 2017
Many aspects of cellular physiology, including cellular response to genotoxic stress, are related to the circadian rhythmicity induced by the molecular clock.
Barbieri, Vito   +4 more
core   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

open access: yesAdvanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

Dopamine D3 receptors inhibit hippocampal gamma oscillations by disturbing CA3 pyramidal cell firing synchrony

open access: yesFrontiers in Pharmacology, 2016
Cortical gamma oscillations are associated with cognitive processes and are altered in several neuropsychiatric conditions such as schizophrenia and Alzheimer’s disease.
Clément E. Lemercier   +4 more
doaj   +1 more source

Respiration organizes gamma synchrony in the prefronto-thalamic network

open access: yesScientific Reports, 2023
Multiple cognitive operations are associated with the emergence of gamma oscillations in the medial prefrontal cortex (mPFC) although little is known about the mechanisms that control this rhythm. Using local field potential recordings from cats, we show
Diellor Basha   +3 more
doaj   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

Scalp Electroencephalogram-Derived Involvement Indexes during a Working Memory Task Performed by Patients with Epilepsy

open access: yesSensors
Electroencephalography (EEG) wearable devices are particularly suitable for monitoring a subject’s engagement while performing daily cognitive tasks. EEG information provided by wearable devices varies with the location of the electrodes, the suitable ...
Erica Iammarino   +5 more
doaj   +1 more source

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