Expression and high levels of insertional polymorphism of an endogenous gammaretrovirus lineage in dogs. [PDF]
PLoS Genetics, 2023 Despite the absence of a confirmed exogenously replicating retrovirus in Canis lupus familiaris (C. familiaris), past retroviral infections are evident in the genomes of living animals via the presence of endogenous retroviruses (ERVs).
Abigail S Jarosz +7 more
doaj +6 more sources
Xenotropic Murine Leukemia Virus–related Gammaretrovirus in Respiratory Tract [PDF]
Emerging Infectious Diseases, 2010 Xenotropic murine leukemia virus–related gammaretrovirus (XMRV) has been recently associated with prostate cancer and chronic fatigue syndrome. To identify nucleic acid sequences, we examined respiratory secretions by using PCR.
Nicole Fischer +6 more
doaj +7 more sources
Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation [PDF]
Retrovirology, 2010 XMRV (xenotropic murine leukaemia virus-related virus) is a gammaretrovirus that has been detected in human patients with prostate carcinoma, chronic fatigue syndrome (CFS) and also in a small percentage of clinically healthy individuals.
Denner Joachim
doaj +8 more sources
Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. [PDF]
PLoS Pathogens, 2006 Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer.
Anatoly Urisman +11 more
doaj +6 more sources
Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV. [PDF]
PLoS ONE, 2010 BackgroundThe human exogenous gammaretrovirus XMRV is thought to be implicated in prostate cancer and chronic fatigue syndrome. Besides pressing epidemiologic questions, the elucidation of the tissue and cell tropism of the virus, as well as its ...
Kristin Stieler, Nicole Fischer
doaj +7 more sources
Long-term infection and vertical transmission of a gammaretrovirus in a foreign host species. [PDF]
PLoS ONE, 2012 Increasing evidence has indicated natural transspecies transmission of gammaretroviruses; however, viral-host interactions after initial xeno-exposure remain poorly understood. Potential association of xenotropic murine leukemia virus-related virus (XMRV)
Toshie Sakuma +6 more
doaj +7 more sources
Indian Journal of Pathology and Microbiology, 2015 Background: Gene therapy has been in use to cure hereditary and acquired diseases by incorporating the desired gene into the cells with the help of gammaretroviral vectors.
Ashok Kumar
doaj +6 more sources
Unique Structure and Distinctive Properties of the Ancient and Ubiquitous Gamma-Type Envelope Glycoprotein [PDF]
Viruses, 2023 After the onset of the AIDS pandemic, HIV-1 (genus Lentivirus) became the predominant model for studying retrovirus Env glycoproteins and their role in entry.
Victoria Hogan, Welkin E. Johnson
doaj +2 more sources
The ancient fusogen EnvP(b)1 is expressed in human tissues and its structure informs the evolution of gammaretrovirus envelope proteins [PDF]
bioRxiv, 2020 Host genomes have acquired diversity from viruses through the capture of viral elements, often from endogenous retroviruses (ERVs). These viral elements contribute new transcriptional control elements and new protein encoding genes, and their refinement ...
K. R. McCarthy +6 more
semanticscholar +2 more sources