Results 91 to 100 of about 2,385 (164)

Cholesterol depletion inactivates XMRV and leads to viral envelope protein release from virions: evidence for role of cholesterol in XMRV infection. [PDF]

PLoS ONE, 2012
Membrane cholesterol plays an important role in replication of HIV-1 and other retroviruses. Here, we report that the gammaretrovirus XMRV requires cholesterol and lipid rafts for infection and replication.
Yuyang Tang, Alvin George, Thyneice Taylor, James E K Hildreth   +3 more
doaj   +1 more source

BET Inhibitor JQ1 Attenuates Feline Leukemia Virus DNA, Provirus, and Antigen Production in Domestic Cat Cell Lines

Viruses, 2023
Feline leukemia virus (FeLV) is a cosmopolitan gammaretrovirus that causes lifelong infections and fatal diseases, including leukemias, lymphomas, immunodeficiencies, and anemias, in domestic and wild felids.
Garrick M. Moll, Cheryl L. Swenson, Vilma Yuzbasiyan-Gurkan   +2 more
doaj   +1 more source

Effects of reticuloendotheliosis virus infection on cytokine production in SPF chickens. [PDF]

PLoS ONE, 2013
Infection with reticuloendotheliosis virus (REV), a gammaretrovirus in the Retroviridae family, can result in immunosuppression and subsequent increased susceptibility to secondary infections.
Mei Xue, Xingming Shi, Yan Zhao, Hongyu Cui, Shunlei Hu, Xianlan Cui, Yunfeng Wang   +6 more
doaj   +1 more source

Vírus da leucemia felina: análise da classificação da infecção, das técnicas de diagnóstico e da eficácia da vacinação com o emprego de técnicas sensíveis de detecção viral Feline leukemia virus: infection outcomes, diagnostic techniques and vaccine efficacy analysis employing sensitive techniques of virus detection

Ciência Rural, 2011
O Vírus da leucemia felina (FeLV) pertence à família Retroviridae, gênero Gammaretrovirus. Diferentemente de outras retroviroses, uma parcela dos gatos jovens e adultos exposta ao FeLV não apresenta antigenemia/viremia, de acordo com as técnicas ...
Andreza Soriano Figueiredo, João Pessoa Araújo Júnior   +1 more
doaj   +1 more source

Mining metagenomes and metatranscriptomes unveils viruses associated with cutaneous squamous cell carcinoma in hematopoietic stem cell transplant recipients

Microbiology Spectrum
We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).
Jana K. Dickter, Yuqi Zhao, Vishwas Parekh, Huiyan Ma, Badri G. Modi, Wai-Yee Li, Saro H. Armenian, Xiwei Wu, Farah R. Abdulla   +8 more
doaj   +1 more source

Failure to Detect XMRV-Specific Antibodies in the Plasma of CFS Patients Using Highly Sensitive Chemiluminescence Immunoassays

Advances in Virology, 2011
In 2009, Lombardi et al. reported their startling finding that the gammaretrovirus xenotropic murine leukemia virus-related retrovirus (XMRV) is present in 67% of blood samples of patients suffering from chronic fatigue syndrome (CFS), as opposed to only
Brendan Oakes, Xiaoxing Qiu, Susan Levine, John Hackett, Brigitte T. Huber   +4 more
doaj   +1 more source

Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics.

PLoS ONE, 2016
Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails ...
Kathryn L Gilroy, Anne Terry, Asif Naseer, Jeroen de Ridder, Amin Allahyar, Weiwei Wang, Eric Carpenter, Andrew Mason, Gane K-S Wong, Ewan R Cameron, Anna Kilbey, James C Neil   +11 more
doaj   +1 more source

Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors

eLife, 2017
Endogenous retroviral sequences provide a molecular fossil record of ancient infections whose analysis might illuminate mechanisms of viral extinction.
Daniel Blanco-Melo, Robert J Gifford, Paul D Bieniasz   +2 more
doaj   +1 more source

The base excision repair pathway is required for efficient lentivirus integration.

PLoS ONE, 2011
An siRNA screen has identified several proteins throughout the base excision repair (BER) pathway of oxidative DNA damage as important for efficient HIV infection.
Kristine E Yoder, Amy Espeseth, Xiao-hong Wang, Qingming Fang, Maria Teresa Russo, R Stephen Lloyd, Daria Hazuda, Robert W Sobol, Richard Fishel   +8 more
doaj   +1 more source

ESCRT Requirements for Murine Leukemia Virus Release

Viruses, 2016
The Murine Leukemia Virus (MLV) is a gammaretrovirus that hijack host components of the endosomal sorting complex required for transport (ESCRT) for budding.
Christina Bartusch, Reinhild Prange
doaj   +1 more source