Results 91 to 100 of about 4,044 (208)

Transcriptional Profiling of Host Gene Expression in Chicken Embryo Fibroblasts Infected with Reticuloendotheliosis Virus Strain HA1101. [PDF]

PLoS ONE, 2015
Reticuloendotheliosis virus (REV), a member of the Gammaretrovirus genus in the Retroviridae family, causes an immunosuppressive, oncogenic and runting-stunting syndrome in multiple avian hosts.
Ji Miao, Yanqing Bao, Jianqiang Ye, Hongxia Shao, Kun Qian, Aijian Qin   +5 more
doaj   +1 more source

The xenotropic murine leukemia virus-related retrovirus debate continues at first international workshop

Retrovirology, 2010
The 1st International Workshop on Xenotropic Murine Leukemia Virus-Related Retrovirus (XMRV), co-sponsored by the National Institutes of Health, The Department of Health and Human Services and Abbott Diagnostics, was convened on September 7/8, 2010 on ...
Boucher Charles A, Silverman Robert H, Stoye Jonathan P, Le Grice Stuart FJ   +3 more
doaj   +1 more source

Endogenous Retrovirus‐Like Particle‐Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell‐Surface Expression of Retroviral Envelope Protein

Biotechnology and Bioengineering, Volume 122, Issue 11, Page 3192-3204, November 2025.
ABSTRACT Despite evidence that they are not functional or infective, retrovirus‐like particles (RVLPs), originating from endogenous proviral sequences in Chinese hamster ovary (CHO) cells, present a safety risk for biotherapeutics manufactured using this cell line due to their resemblance to other mammalian leukemia viruses.
Matthew Stuible, Sergio P. Alpuche‐Lazcano, Christian Gervais, Manon Ouimet, Julie Lippens, Martine Pagé, Audrey Morasse, Anna N. Moraitis, Yves Durocher   +8 more
wiley   +1 more source

Analysis of XMRV integration sites from human prostate cancer tissues suggests PCR contamination rather than genuine human infection

Retrovirology, 2011
XMRV is a gammaretrovirus associated in some studies with human prostate cancer and chronic fatigue syndrome. Central to the hypothesis of XMRV as a human pathogen is the description of integration sites in DNA from prostate tumour tissues.
Kellam Paul, Garson Jeremy A, Towers Greg J   +2 more
doaj   +1 more source

The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]

, 2015
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M, Campo-Fernandez, Beatriz, Cooper, Aaron R, Hoban, Megan D, Hollis, Roger P, Kaufman, Michael L, Kohn, Donald B, Lumaquin, Dianne, Romero, Zulema, Senadheera, Shantha, Urbinati, Fabrizia, Wang, Xiaoyan, Wherley, Jennifer   +12 more
core   +4 more sources

Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management

Australian Veterinary Journal, Volume 103, Issue 10, Page 617-635, October 2025.
Progressive feline leukaemia virus (FeLV) infection dramatically shortens the lives of infected cats, causing acquired immunodeficiency, aplastic anaemia, lymphoma, leukaemia and other myeloproliferative diseases. The potential impact of regressive FeLV infection on the development of disease remains largely unknown, although there is evidence it ...
ME Westman, SJ Coggins, M van Dorsselaer, JM Norris, RA Squires, M Thompson, R Malik   +6 more
wiley   +1 more source

Disease-associated XMRV sequences are consistent with laboratory contamination [PDF]

, 2010
BACKGROUND: Xenotropic murine leukaemia viruses (MLV-X) are endogenous gammaretroviruses that infect cells from many species, including humans. Xenotropic murine leukaemia virus-related virus (XMRV) is a retrovirus that has been the subject of intense ...
Andrew Futreal, Aris Katzourakis, Astrid Gall, Charlotte J Houldcroft, Choon Ping Tan, Deenan Pillay, Eleanor R Gray, Greg J Towers, Jeremy A Garson, Oliver G Pybus, Paul Kellam, Stephane Hue, Stuart McLaren   +12 more
core   +5 more sources

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Literature review : analysis of genomic variation and evolution of Fb, a group of human endogenous retroviruses [PDF]

, 2018
[Resumen]: El grupo de retrovirus endógenos humanos HERV-Fb1, perteneciente al grupo de los gammaretrovirus (grupo I) presenta algunas características que lo diferencian de los demás grupos. Este retrovirus es el precursor de la supresina.
Touzón Fernández, María del Carmen
core  

HERV Modulation in Colorectal Carcinoma Patients: A Snapshot of Endogenous Retroviral Transcriptome

Journal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT Human endogenous retroviruses (HERVs) are proviral relics of infections that affected primates' germ line. Many HERV elements retain a residual capacity to encode transcripts and proteins that have been occasionally domesticated for the host physiology.
Nicole Grandi, Ching‐Hsuan Liu, Saili Chabukswar, Daniele Carta, Yun Yen, Liang‐Tzung Lin, Enzo Tramontano   +6 more
wiley   +1 more source