Results 141 to 150 of about 2,385 (164)

Computational and theoretical insights into the cytotoxic prospects of compounds isolated from Elaeodendron buchananii against Leukemia. [PDF]

Toxicol Rep
Erukainure OL, Nambooze J, Chukwuma CI, Malloum A, Aljoundi A, Elamin G.   +5 more
europepmc   +1 more source

Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting. [PDF]

Biomolecules
Rizatdinova SN, Ershova AE, Astrakhantseva IV.   +2 more
europepmc   +1 more source

Novel gene manipulation approaches to unlock the existing bottlenecks of CAR-NK cell therapy. [PDF]

Front Cell Dev Biol
Dehghan F, Metanat Y, Askarizadeh M, Ahmadi E, Moradi V.   +4 more
europepmc   +1 more source

The viral landscape in metastatic solid cancers. [PDF]

Heliyon
Mjelle R, Castro Í, Aass KR.
europepmc   +1 more source

Gut virome and its implications in the pathogenesis and therapeutics of inflammatory bowel disease. [PDF]

BMC Med
Wu Y, Cheng R, Lin H, Li L, Jia Y, Philips A, Zuo T, Zhang H.   +7 more
europepmc   +1 more source

Human Endogenous Retroviruses in Breast Cancer: Altered Expression Pattern Implicates Divergent Roles in Carcinogenesis.

Oncology
Záveský L, Jandáková E, Weinberger V, Minář L, Kohoutová M, Slanař O.   +5 more
europepmc   +1 more source

Insight into the epigenetic landscape of a currently endogenizing gammaretrovirus in mule deer (Odocoileus hemionus).

Genomics, 2019
Endogenous retroviruses (ERVs) constitute a significant part of vertebrate genomes. They originated from past retroviral infections and some of them retain transcriptional activity. The key mechanism avoiding uncontrolled ERV transcription is DNA methylation-mediated epigenetic silencing.
T. Hron, H. Fábryová, D. Elleder
semanticscholar   +6 more sources

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Silencing and variegation of gammaretrovirus and lentivirus vectors.

Human Gene Therapy, 2005
Retrovirus vectors integrate into the genome, providing stable gene transfer, but integration contributes in part to transcriptional silencing that compromises long-term expression.
J. Ellis
semanticscholar   +4 more sources

Prevalence of human gammaretrovirus XMRV in sporadic prostate cancer. [PDF]

Journal of Clinical Virology, 2008
We previously identified a novel exogenous gammaretrovirus (xenotropic murine leukemia virus-related gammaretrovirus (XMRV)) using a pan-viral microarray. XMRV is the first MLV-related virus found in human infection. Forty percent (8/20) of familial prostate cancer patients homozygous for a mutation in RNase L (R462Q) were positive for XMRV, while the ...
N. Fischer, O. Hellwinkel, C. Schulz, F. Chun, H. Huland, M. Aepfelbacher, T. Schlomm   +6 more
semanticscholar   +4 more sources

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.

Virology, 2010
Recently, the first human infection with an exogenous gammaretrovirus (XMRV) was reported. In its initial description, XMRV was confined to prostate stromal fibroblasts, although subsequent reports demonstrated XMRV protein expression in prostate epithelial cells.
K. Stieler, C. Schulz, M. Lavanya, M. Aepfelbacher, C. Stocking, N. Fischer   +5 more
semanticscholar   +4 more sources